Intensive care unit outcomes among patients with lung cancer in the surveillance, epidemiology, and end results-medicare registry

Christopher G. Slatore, Laura M. Cecere, Jennifer L. LeTourneau, Maya O'Neil, Jonathan P. Duckart, Renda Soylemez Wiener, Farhood Farjah, Colin R. Cooke

Research output: Contribution to journalArticle

55 Scopus citations


Purpose: Lung cancer is the leading cause of cancer-related mortality. Intensive care unit (ICU) use among patients with cancer is increasing, but data regarding ICU outcomes for patients with lung cancer are limited. Patients and Methods: We used the Surveillance, Epidemiology, and End Results (SEER) -Medicare registry (1992 to 2007) to conduct a retrospective cohort study of patients with lung cancer who were admitted to an ICU for reasons other than surgical resection of their tumor. We used logistic and Cox regression to evaluate associations of patient characteristics and hospital mortality and 6-month mortality, respectively. We calculated adjusted associations for mechanical ventilation receipt with hospital and 6-month mortality. Results: Of the 49,373 patients with lung cancer admitted to an ICU for reasons other than surgical resection, 76% of patients survived the hospitalization, and 35% of patients were alive 6 months after discharge. Receipt of mechanical ventilation was associated with increased hospital mortality (adjusted odds ratio, 6.95;95%CI, 6.89 to 7.01; P

Original languageEnglish (US)
Pages (from-to)1686-1691
Number of pages6
JournalJournal of Clinical Oncology
Issue number14
Publication statusPublished - May 10 2012


ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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