Intensive care unit outcomes among patients with lung cancer in the surveillance, epidemiology, and end results-medicare registry

Christopher G. Slatore, Laura M. Cecere, Jennifer L. LeTourneau, Maya O'Neil, Jonathan P. Duckart, Renda Soylemez Wiener, Farhood Farjah, Colin R. Cooke

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Purpose: Lung cancer is the leading cause of cancer-related mortality. Intensive care unit (ICU) use among patients with cancer is increasing, but data regarding ICU outcomes for patients with lung cancer are limited. Patients and Methods: We used the Surveillance, Epidemiology, and End Results (SEER) -Medicare registry (1992 to 2007) to conduct a retrospective cohort study of patients with lung cancer who were admitted to an ICU for reasons other than surgical resection of their tumor. We used logistic and Cox regression to evaluate associations of patient characteristics and hospital mortality and 6-month mortality, respectively. We calculated adjusted associations for mechanical ventilation receipt with hospital and 6-month mortality. Results: Of the 49,373 patients with lung cancer admitted to an ICU for reasons other than surgical resection, 76% of patients survived the hospitalization, and 35% of patients were alive 6 months after discharge. Receipt of mechanical ventilation was associated with increased hospital mortality (adjusted odds ratio, 6.95;95%CI, 6.89 to 7.01; P

Original languageEnglish (US)
Pages (from-to)1686-1691
Number of pages6
JournalJournal of Clinical Oncology
Volume30
Issue number14
DOIs
StatePublished - May 10 2012

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Medicare
Intensive Care Units
Registries
Lung Neoplasms
Epidemiology
Hospital Mortality
Artificial Respiration
Mortality
Neoplasms
Hospitalization
Cohort Studies
Retrospective Studies
Logistic Models
Odds Ratio

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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Intensive care unit outcomes among patients with lung cancer in the surveillance, epidemiology, and end results-medicare registry. / Slatore, Christopher G.; Cecere, Laura M.; LeTourneau, Jennifer L.; O'Neil, Maya; Duckart, Jonathan P.; Wiener, Renda Soylemez; Farjah, Farhood; Cooke, Colin R.

In: Journal of Clinical Oncology, Vol. 30, No. 14, 10.05.2012, p. 1686-1691.

Research output: Contribution to journalArticle

Slatore, Christopher G. ; Cecere, Laura M. ; LeTourneau, Jennifer L. ; O'Neil, Maya ; Duckart, Jonathan P. ; Wiener, Renda Soylemez ; Farjah, Farhood ; Cooke, Colin R. / Intensive care unit outcomes among patients with lung cancer in the surveillance, epidemiology, and end results-medicare registry. In: Journal of Clinical Oncology. 2012 ; Vol. 30, No. 14. pp. 1686-1691.
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