Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States

Derek LeRoith, Charles Roberts

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The insulin-like growth factor system, which includes the IGFs, IGF-binding proteins and IGF receptors, plays an essential role in normal growth and development, as well as the cellular differentiation of a number of other important systems, including the reproductive and immune systems. IGF action has also been implicated in several pathological conditions, including tissue repair, malnutrition, diabetes and malignancy.

Original languageEnglish (US)
Pages (from-to)251-256
Number of pages6
JournalJournal of Pediatric Endocrinology and Metabolism
Volume6
Issue number3-4
DOIs
StatePublished - 1993
Externally publishedYes

Fingerprint

Somatomedin Receptors
Insulin-Like Growth Factor Binding Proteins
Somatomedins
Growth and Development
Malnutrition
Immune System
Neoplasms

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Pediatrics, Perinatology, and Child Health

Cite this

Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States. / LeRoith, Derek; Roberts, Charles.

In: Journal of Pediatric Endocrinology and Metabolism, Vol. 6, No. 3-4, 1993, p. 251-256.

Research output: Contribution to journalArticle

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