Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States

Derek LeRoith, Charles T. Roberts

    Research output: Contribution to journalArticle

    15 Scopus citations

    Abstract

    The insulin-like growth factor system, which includes the IGFs, IGF-binding proteins and IGF receptors, plays an essential role in normal growth and development, as well as the cellular differentiation of a number of other important systems, including the reproductive and immune systems. IGF action has also been implicated in several pathological conditions, including tissue repair, malnutrition, diabetes and malignancy.

    Original languageEnglish (US)
    Pages (from-to)251-256
    Number of pages6
    JournalJournal of Pediatric Endocrinology and Metabolism
    Volume6
    Issue number3-4
    DOIs
    StatePublished - Jul 1993

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Endocrinology, Diabetes and Metabolism
    • Endocrinology

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