Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States

Derek LeRoith; Charles T. Roberts

doi:10.1515/JPEM.1993.6.3-4.251

Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States

Derek LeRoith, Charles T. Roberts

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The insulin-like growth factor system, which includes the IGFs, IGF-binding proteins and IGF receptors, plays an essential role in normal growth and development, as well as the cellular differentiation of a number of other important systems, including the reproductive and immune systems. IGF action has also been implicated in several pathological conditions, including tissue repair, malnutrition, diabetes and malignancy.

Original language	English (US)
Pages (from-to)	251-256
Number of pages	6
Journal	Journal of Pediatric Endocrinology and Metabolism
Volume	6
Issue number	3-4
DOIs	https://doi.org/10.1515/JPEM.1993.6.3-4.251
State	Published - Jul 1993
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1515/JPEM.1993.6.3-4.251

Cite this

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title = "Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States",

abstract = "The insulin-like growth factor system, which includes the IGFs, IGF-binding proteins and IGF receptors, plays an essential role in normal growth and development, as well as the cellular differentiation of a number of other important systems, including the reproductive and immune systems. IGF action has also been implicated in several pathological conditions, including tissue repair, malnutrition, diabetes and malignancy.",

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year = "1993",

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AB - The insulin-like growth factor system, which includes the IGFs, IGF-binding proteins and IGF receptors, plays an essential role in normal growth and development, as well as the cellular differentiation of a number of other important systems, including the reproductive and immune systems. IGF action has also been implicated in several pathological conditions, including tissue repair, malnutrition, diabetes and malignancy.

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ER -

Insulin-Like Growth Factors and Their Receptors in Normal Physiology and Pathological States

Abstract

ASJC Scopus subject areas

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