Insulin-like growth factor-I in growth and metabolism

P. Backeljauw, P. Bang, D. B. Dunger, A. Juul, Y. Le Bouc, R. Rosenfeld

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Deficiency of insulin-like growth factor-I (IGF-I) results in growth failure. A variety of molecular defects have been found to underlie severe primary IGF-I deficiency (IGFD), in which serum IGF-I concentrations are substantially decreased and fail to respond to GH therapy. Identification of more patients with primary or secondary IGFD is likely with investigative and diagnostic progress, particularly in the assessment of

Original languageEnglish (US)
Pages (from-to)3-16
Number of pages14
JournalJournal of Pediatric Endocrinology and Metabolism
Issue number1-2
StatePublished - Jan 1 2010


  • Growth
  • Igf-i deficiency
  • Insulin-like growth factor-i
  • Metabolism
  • Severe insulin resistance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Fingerprint Dive into the research topics of 'Insulin-like growth factor-I in growth and metabolism'. Together they form a unique fingerprint.

Cite this