Insight and neurocognitive functioning in bipolar subjects

Mujeeb Shad, Konasale Prasad, Steven D. Forman, Gretchen L. Haas, Jon D. Walker, Liubomir A. Pisarov, Gerald Goldstein

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background Insight concerning having a mental illness has been found to influence outcome and effectiveness of treatment. It has been studied mainly in the area of schizophrenia with few studies addressing other disorders. This study evaluates insight in individuals with bipolar disorder using the Scale to Assess Unawareness of Mental Disorder (SUMD), a comprehensive interview for evaluation of awareness of illness and attribution of symptoms. The hypothesis was that in bipolar disorder level of awareness may be associated with numerous factors including neurocognitive function, structural changes in the frontal lobes and hippocampus evaluated by MRI, neurocognitive status, severity of mania and other psychiatric symptoms and comorbid alcoholism. Method In order to evaluate this hypothesis 33 individuals with DSM-IV diagnosed bipolar disorder, some with and some without comorbid alcoholism, were administered the SUMD and a number of other procedures including a quantitative MRI measuring volume of the frontal lobes and hippocampus, a brief battery of neurocognitive tests, the Brief Psychiatric Rating Scale, and the Young Mania Rating Scale. The data were analyzed by comparing participants with and without alcoholism on these procedures using t tests and by linear multiple regression, with SUMD ratings of awareness and attribution as the dependent variables and variable sets from the other procedures administered as multivariate independent variables. Results The median score obtained from the SUMD for current awareness was in a range between full awareness and uncertainty concerning presence of a mental disorder. For attribution, the median score indicated that attribution was usually made to the illness itself. None of the differences between participants with and without comorbid alcoholism were significant for the SUMD awareness and attribution scores, neurocognitive or MRI variables. The multiple regression analyses only showed a significant degree of association between the SUMD awareness score and the Young Mania Rating Scale (r2 =.632, p

Original languageEnglish (US)
Pages (from-to)112-120
Number of pages9
JournalComprehensive Psychiatry
Volume56
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Bipolar Disorder
Alcoholism
Frontal Lobe
Mental Disorders
Hippocampus
Brief Psychiatric Rating Scale
Diagnostic and Statistical Manual of Mental Disorders
Uncertainty
Psychiatry
Linear Models
Schizophrenia
Regression Analysis
Interviews

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Medicine(all)

Cite this

Shad, M., Prasad, K., Forman, S. D., Haas, G. L., Walker, J. D., Pisarov, L. A., & Goldstein, G. (2015). Insight and neurocognitive functioning in bipolar subjects. Comprehensive Psychiatry, 56, 112-120. https://doi.org/10.1016/j.comppsych.2014.04.016

Insight and neurocognitive functioning in bipolar subjects. / Shad, Mujeeb; Prasad, Konasale; Forman, Steven D.; Haas, Gretchen L.; Walker, Jon D.; Pisarov, Liubomir A.; Goldstein, Gerald.

In: Comprehensive Psychiatry, Vol. 56, 01.01.2015, p. 112-120.

Research output: Contribution to journalArticle

Shad, M, Prasad, K, Forman, SD, Haas, GL, Walker, JD, Pisarov, LA & Goldstein, G 2015, 'Insight and neurocognitive functioning in bipolar subjects', Comprehensive Psychiatry, vol. 56, pp. 112-120. https://doi.org/10.1016/j.comppsych.2014.04.016
Shad, Mujeeb ; Prasad, Konasale ; Forman, Steven D. ; Haas, Gretchen L. ; Walker, Jon D. ; Pisarov, Liubomir A. ; Goldstein, Gerald. / Insight and neurocognitive functioning in bipolar subjects. In: Comprehensive Psychiatry. 2015 ; Vol. 56. pp. 112-120.
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