Inhibition of Ocular Herpes Simplex Infection in Rabbits by Extracts of Burkitt's Lymphoma Cell Cultures

Daniel M. Albert, Alan S. Rabson

Research output: Contribution to journalArticle

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Abstract

Extracts of Burkitt's lymphoma cell cultures which had been previously shown to contain an inhibitor of herpes simplex virus in vitro were used to treat rabbits with ocular herpes infection. Topical instillation of the extract into the eyes of the rabbits cured or suppressed the progression of herpetic keratitis. Histopathologic studies of the eyes of treated and control animals confirmed the inhibition of keratitis and other evidence of herpes-related ocular inflammation.

Original languageEnglish (US)
Pages (from-to)108-111
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume138
Issue number1
DOIs
StatePublished - Oct 1971

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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