Influence of cadmium on caries and the cariostatic properties of fluoride in rats

Thomas (Tom) Shearer, J. L. Britton, D. J. DeSart, J. R. Johnson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effects of fluoridated drinking water in both male and female rats. The mechanism for the caries-promoting properties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto erupted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.

Original languageEnglish (US)
Pages (from-to)176-180
Number of pages5
JournalArchives of Environmental Health
Volume35
Issue number3
StatePublished - 1980

Fingerprint

Cadmium
Fluorides
fluoride
Rats
cadmium
enamel
Enamels
Dental Enamel
Dentin
Ashes
Cariostatic Agents
Drinking Water
tooth
Tooth
ash
calcium
drinking water
Calcium
Injections

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health

Cite this

Influence of cadmium on caries and the cariostatic properties of fluoride in rats. / Shearer, Thomas (Tom); Britton, J. L.; DeSart, D. J.; Johnson, J. R.

In: Archives of Environmental Health, Vol. 35, No. 3, 1980, p. 176-180.

Research output: Contribution to journalArticle

Shearer, Thomas (Tom) ; Britton, J. L. ; DeSart, D. J. ; Johnson, J. R. / Influence of cadmium on caries and the cariostatic properties of fluoride in rats. In: Archives of Environmental Health. 1980 ; Vol. 35, No. 3. pp. 176-180.
@article{4533a19d40db4a4abc9723cab5624053,
title = "Influence of cadmium on caries and the cariostatic properties of fluoride in rats",
abstract = "Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effects of fluoridated drinking water in both male and female rats. The mechanism for the caries-promoting properties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto erupted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.",
author = "Shearer, {Thomas (Tom)} and Britton, {J. L.} and DeSart, {D. J.} and Johnson, {J. R.}",
year = "1980",
language = "English (US)",
volume = "35",
pages = "176--180",
journal = "Archives of Environmental and Occupational Health",
issn = "1933-8244",
publisher = "Heldref Publications",
number = "3",

}

TY - JOUR

T1 - Influence of cadmium on caries and the cariostatic properties of fluoride in rats

AU - Shearer, Thomas (Tom)

AU - Britton, J. L.

AU - DeSart, D. J.

AU - Johnson, J. R.

PY - 1980

Y1 - 1980

N2 - Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effects of fluoridated drinking water in both male and female rats. The mechanism for the caries-promoting properties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto erupted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.

AB - Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effects of fluoridated drinking water in both male and female rats. The mechanism for the caries-promoting properties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto erupted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.

UR - http://www.scopus.com/inward/record.url?scp=0018875493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018875493&partnerID=8YFLogxK

M3 - Article

C2 - 7387197

AN - SCOPUS:0018875493

VL - 35

SP - 176

EP - 180

JO - Archives of Environmental and Occupational Health

JF - Archives of Environmental and Occupational Health

SN - 1933-8244

IS - 3

ER -