Inferior Petrosal Venous Sinus Sampling in Lateralization of ACTH-Secreting Pituitary Microadenomas

Martin J. Hendriks, Johanna W. Van 't Verlaat, Hans Pf Koppeschaar, Ronald J.m. Croughs, Edward H. Oldfield, George P. Chrousos, Lynnette K. Nieman, Gordon B. Cutler, Marcus Schaaf, D. Lynn Loriaux, John L. Doppman

Research output: Contribution to journalLetterpeer-review

2 Scopus citations

Abstract

To the Editor: In their article in the January 10th issue of the Journal, Oldfield et al.1 proposed that simultaneous bilateral sampling of blood from the inferior petrosal venous sinus provides a means of localizing an ACTH-secreting microadenoma to one side of the pituitary gland. They state that “Unfortunately, radiographic studies only occasionally reveal the site of a microadenoma.” Of the 12 patients with confirmed pituitary-dependent hypercortisolism, only 3 (1 with a macroadenoma and 2 with microadenomas) had abnormalities on skull x-ray films, CT scans, or both. In the discussion the authors refer to an article by Turski et.

Original languageEnglish (US)
Pages (from-to)1457-1458
Number of pages2
JournalNew England Journal of Medicine
Volume312
Issue number22
DOIs
StatePublished - May 30 1985
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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