Infection prophylaxis

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Infections remain an important cause of non-relapse mortality in HSCT recipients. Specific risk for infection is related to prior exposure history (e.g., relapse of latent infection), intensity of conditioning regimens and immunosuppression, and new exposures in the setting of altered host immune response. Prevention of infection by prophylactic and preemptive strategies has been associated with improvement in transplant outcomes over the past few decades. The introduction of new oral antivirals (e.g., valganciclovir) and antifungal compounds (e.g., posaconazole, voriconazole) in the past decade has allowed for a less toxic and more facile approach to infection prevention.

Original languageEnglish (US)
Title of host publicationBlood and Marrow Transplant Handbook
Subtitle of host publicationComprehensive Guide for Patient Care
PublisherSpringer New York
Pages71-82
Number of pages12
ISBN (Print)9781441975058
DOIs
StatePublished - Dec 1 2011

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Strasfeld, L. (2011). Infection prophylaxis. In Blood and Marrow Transplant Handbook: Comprehensive Guide for Patient Care (pp. 71-82). Springer New York. https://doi.org/10.1007/978-1-4419-7506-5_8