Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction

Christina R. Robinson, Justin L. Martin, Lily Zhang, Russell M. Canham, Shuaib M. Abdullah, Joaquin E. Cigarroa, L. David Hillis, Sabina A. Murphy, Darren K. McGuire, James A. De Lemos, Ellen C. Keeley

    Research output: Contribution to journalArticle

    11 Scopus citations

    Abstract

    In patients who have ST-segment elevation myocardial infarction (STEMI), a patent infarct-related artery on the initial angiogram is associated with improved clinical outcomes, including decreased mortality. The present study assessed the influence of administering aspirin, β blockers, statins, and angiotensin-converting enzyme inhibitors before STEMI on infarct-related artery patency. Our data demonstrate that patients who have STEMI and receive these medications on an outpatient basis before the event have a higher likelihood of having a patent infarct-related artery compared with patients who do not receive these medications. Further, our data demonstrate a graded association according to the number of such medications being administered: the likelihood of a patent infarct-related artery increased to >50% as the number of these medications increased.

    Original languageEnglish (US)
    Pages (from-to)7-9
    Number of pages3
    JournalAmerican Journal of Cardiology
    Volume97
    Issue number1
    DOIs
    StatePublished - Jan 1 2006

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

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  • Cite this

    Robinson, C. R., Martin, J. L., Zhang, L., Canham, R. M., Abdullah, S. M., Cigarroa, J. E., Hillis, L. D., Murphy, S. A., McGuire, D. K., De Lemos, J. A., & Keeley, E. C. (2006). Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction. American Journal of Cardiology, 97(1), 7-9. https://doi.org/10.1016/j.amjcard.2005.07.103