Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity

Carine H. Wouters; Tammy M. Martin; Dorothee Stichweh; Marilynn Punaro; Trudy M. Doyle; Jinnell A. Lewis; Pierre Quartier; Carlos D. Rose

doi:10.1016/j.jpeds.2007.08.005

Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity

Carine H. Wouters, Tammy M. Martin, Dorothee Stichweh, Marilynn Punaro, Trudy M. Doyle, Jinnell A. Lewis, Pierre Quartier, Carlos D. Rose

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We report on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation, recruited through the International Registry of Pediatric Granulomatous Arthritis. Neither CARD15 nor CIAS1 mutations were found. Despite immunosuppressive therapy, disease course was progressive. Response to anti-tumor necrosis factor monoclonal antibody in 3 patients is of note.

Original language	English (US)
Pages (from-to)	707-709
Number of pages	3
Journal	Journal of Pediatrics
Volume	151
Issue number	6
DOIs	https://doi.org/10.1016/j.jpeds.2007.08.005
State	Published - Dec 2007

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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title = "Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity",

abstract = "We report on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation, recruited through the International Registry of Pediatric Granulomatous Arthritis. Neither CARD15 nor CIAS1 mutations were found. Despite immunosuppressive therapy, disease course was progressive. Response to anti-tumor necrosis factor monoclonal antibody in 3 patients is of note.",

author = "Wouters, {Carine H.} and Martin, {Tammy M.} and Dorothee Stichweh and Marilynn Punaro and Doyle, {Trudy M.} and Lewis, {Jinnell A.} and Pierre Quartier and Rose, {Carlos D.}",

note = "Funding Information: Supported by a Career Development Award from The Research to Prevent Blindness, by NIH grant EY013139, and by the Gerlinger Award, Oregon Health Foundation. ",

year = "2007",

month = dec,

doi = "10.1016/j.jpeds.2007.08.005",

language = "English (US)",

volume = "151",

pages = "707--709",

journal = "Journal of Pediatrics",

issn = "0022-3476",

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TY - JOUR

T1 - Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis

T2 - A New Clinicopathologic Entity

AU - Wouters, Carine H.

AU - Martin, Tammy M.

AU - Stichweh, Dorothee

AU - Punaro, Marilynn

AU - Doyle, Trudy M.

AU - Lewis, Jinnell A.

AU - Quartier, Pierre

AU - Rose, Carlos D.

N1 - Funding Information: Supported by a Career Development Award from The Research to Prevent Blindness, by NIH grant EY013139, and by the Gerlinger Award, Oregon Health Foundation.

PY - 2007/12

Y1 - 2007/12

N2 - We report on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation, recruited through the International Registry of Pediatric Granulomatous Arthritis. Neither CARD15 nor CIAS1 mutations were found. Despite immunosuppressive therapy, disease course was progressive. Response to anti-tumor necrosis factor monoclonal antibody in 3 patients is of note.

AB - We report on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation, recruited through the International Registry of Pediatric Granulomatous Arthritis. Neither CARD15 nor CIAS1 mutations were found. Despite immunosuppressive therapy, disease course was progressive. Response to anti-tumor necrosis factor monoclonal antibody in 3 patients is of note.

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JO - Journal of Pediatrics

JF - Journal of Pediatrics

IS - 6

ER -

Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity

Abstract

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