Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis

A New Clinicopathologic Entity

Carine H. Wouters, Tammy Martin, Dorothee Stichweh, Marilynn Punaro, Trudy M. Doyle, Jinnell A. Lewis, Pierre Quartier, Carlos D. Rose

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We report on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation, recruited through the International Registry of Pediatric Granulomatous Arthritis. Neither CARD15 nor CIAS1 mutations were found. Despite immunosuppressive therapy, disease course was progressive. Response to anti-tumor necrosis factor monoclonal antibody in 3 patients is of note.

Original languageEnglish (US)
Pages (from-to)707-709
Number of pages3
JournalJournal of Pediatrics
Volume151
Issue number6
DOIs
StatePublished - Dec 2007

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Panniculitis
Uveitis
Immunosuppressive Agents
Registries
Fever
Tumor Necrosis Factor-alpha
Monoclonal Antibodies
Inflammation
Mutation
Therapeutics
Blau syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis : A New Clinicopathologic Entity. / Wouters, Carine H.; Martin, Tammy; Stichweh, Dorothee; Punaro, Marilynn; Doyle, Trudy M.; Lewis, Jinnell A.; Quartier, Pierre; Rose, Carlos D.

In: Journal of Pediatrics, Vol. 151, No. 6, 12.2007, p. 707-709.

Research output: Contribution to journalArticle

Wouters, CH, Martin, T, Stichweh, D, Punaro, M, Doyle, TM, Lewis, JA, Quartier, P & Rose, CD 2007, 'Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity', Journal of Pediatrics, vol. 151, no. 6, pp. 707-709. https://doi.org/10.1016/j.jpeds.2007.08.005
Wouters, Carine H. ; Martin, Tammy ; Stichweh, Dorothee ; Punaro, Marilynn ; Doyle, Trudy M. ; Lewis, Jinnell A. ; Quartier, Pierre ; Rose, Carlos D. / Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis : A New Clinicopathologic Entity. In: Journal of Pediatrics. 2007 ; Vol. 151, No. 6. pp. 707-709.
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