Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder

D. C. Dawson, Q. Al-Awqati

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

When active Na+ transport across the toad urinary bladder was abolished by ouabain, a 'reversed' short circuit current could be induced by an Na+ concentration gradient. This reversed current was increased by vasopressin and inhibited by amiloride and appears to represent net Na+ movement 'backwards' through epithelial cells which normally participate in active Na+ transport across the bladder.

Original languageEnglish (US)
Pages (from-to)413-417
Number of pages5
JournalBBA - Biomembranes
Volume508
Issue number2
DOIs
StatePublished - Apr 4 1978
Externally publishedYes

Fingerprint

Amiloride
Active Biological Transport
Ouabain
Vasopressins
Short circuit currents
Anura
Urinary Bladder
Epithelial Cells

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Cell Biology
  • Medicine(all)

Cite this

Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder. / Dawson, D. C.; Al-Awqati, Q.

In: BBA - Biomembranes, Vol. 508, No. 2, 04.04.1978, p. 413-417.

Research output: Contribution to journalArticle

Dawson, D. C. ; Al-Awqati, Q. / Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder. In: BBA - Biomembranes. 1978 ; Vol. 508, No. 2. pp. 413-417.
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