Individual-administered human behavioral test batteries to identify neurotoxic chemicals

Wyndham Anger, M. G. Cassitto

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Most research demonstrating behavioral effects of occupational chemical exposures is produced in established laboratories using a consistent set or battery of tests. Exemplifying this tradition are batteries developed at Finland's Institute of Occupational Health, Milan's Institute of Occupational Health, Sweden's National Institute of Occupational Health, Australia's National Institute of Occupational Safety and Health, and at universities in the United States and other countries. In 1983, under the World Health Organization (WHO) aegis, experienced human occupational researchers recommended the Neurobehavioral Core Test Battery (NCTB) as a screening instrument to be administered by an individual to subjects exposed to chemicals believed to be neurotoxic. Health professionals from 50 cities in 27 countries distributed on every large continent have been trained to administer the NCTB according to its Operational Guide. Six issues need to be addressed regarding human-administered test batteries: (a) The critical role of individual-administered batteries to screen chemically exposed populations in a field increasingly dominated by computer-administered batteries; (b) selection criteria for tests to assess known and unknown chemicals; (c) utility of baseline data for study analysis and interpretation; (d) test battery validation; (e) availability and cost of inexpensive test batteries; and (f) equivalence of computer- and human-administered variants of the same tests.

Original languageEnglish (US)
Pages (from-to)93-106
Number of pages14
JournalEnvironmental Research
Volume61
Issue number1
DOIs
StatePublished - 1993

Fingerprint

Occupational Health
Health
National Institute for Occupational Safety and Health (U.S.)
Behavioral Research
National Institutes of Health (U.S.)
Occupational Exposure
Finland
Sweden
Patient Selection
Behavioral research
Research Personnel
Costs and Cost Analysis
Population
Behavior Rating Scale
test
battery
chemical
Screening
World Health Organization
Availability

ASJC Scopus subject areas

  • Environmental Science(all)

Cite this

Individual-administered human behavioral test batteries to identify neurotoxic chemicals. / Anger, Wyndham; Cassitto, M. G.

In: Environmental Research, Vol. 61, No. 1, 1993, p. 93-106.

Research output: Contribution to journalArticle

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