Independent visual threshold measurements in the two eyes of freely moving rats and mice using a virtual-reality optokinetic system

R. M. Douglas, N. M. Alam, B. D. Silver, Trevor McGill, W. W. Tschetter, G. T. Prusky

Research output: Contribution to journalArticle

218 Citations (Scopus)

Abstract

Slow horizontal head and body rotation occurs in mice and rats when the visual field is rotated around them, and these optomotor movements can be produced reliably in a virtual-reality system. If one eye is closed, only motion in the temporal-to-nasal direction for the contralateral eye evokes the tracking response. When the maximal spatial frequency capable of driving the response ("acuity") was measured under monocular and binocular viewing conditions, the monocular acuity was identical to the binocular acuity measured with the same rotation direction. Thus, the visual capabilities of each eye can be measured under binocular conditions simply by changing the direction of rotation. Lesions of the visual cortex had no effect on the acuities measured with the virtual optokinetic system, whereas perceptual thresholds obtained previously with the Visual Water Task are. The optokinetic acuities were also consistently lower than acuity estimates from the Visual Water Task, but contrast sensitivities were the same or better. These data show that head-tracking in a virtual optokinetic drum is driven by subcortical, lower frequency, and contralateral pathways.

Original languageEnglish (US)
Pages (from-to)677-684
Number of pages8
JournalVisual Neuroscience
Volume22
Issue number5
DOIs
StatePublished - Sep 2005
Externally publishedYes

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User-Computer Interface
Head
Contrast Sensitivity
Water
Visual Cortex
Visual Fields
Nose
Visual Acuity
Direction compound

Keywords

  • Accessory optic system
  • Acuity
  • Contrast sensitivity
  • Optomotor
  • Visual cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Independent visual threshold measurements in the two eyes of freely moving rats and mice using a virtual-reality optokinetic system. / Douglas, R. M.; Alam, N. M.; Silver, B. D.; McGill, Trevor; Tschetter, W. W.; Prusky, G. T.

In: Visual Neuroscience, Vol. 22, No. 5, 09.2005, p. 677-684.

Research output: Contribution to journalArticle

Douglas, R. M. ; Alam, N. M. ; Silver, B. D. ; McGill, Trevor ; Tschetter, W. W. ; Prusky, G. T. / Independent visual threshold measurements in the two eyes of freely moving rats and mice using a virtual-reality optokinetic system. In: Visual Neuroscience. 2005 ; Vol. 22, No. 5. pp. 677-684.
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