Abstract
Aim: Timely recruitment of eligible participants is essential for the success of clinical trials, with insufficient accrual being the leading cause for premature termination of both oncology and non-oncology trials. Methods: In this paper we further elaborate on the challenges for patient participation in oncology trials from physician, patient, healthcare system, and some trial-related perspectives. Results: We present strategies such as use of digital healthcare technologies, real-world data and real-world evidence, decentralized clinical trials, pragmatic trial designs, and supportive services to increase patient participation. Conclusions: Multifaceted measures are necessary to increase patient participation, especially for those who are under-represented in cancer trials.
Original language | English (US) |
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Pages (from-to) | 2219-2226 |
Number of pages | 8 |
Journal | Cancer medicine |
Volume | 12 |
Issue number | 3 |
DOIs | |
State | Published - Feb 2023 |
Keywords
- cancer trials
- clinical trials
- patient accrual
- pragmatic clinical trials
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research