Increased vitamin E intake is associated with higher α-tocopherol concentration in the maternal circulation but higher α-carboxyethyl hydroxychroman concentration in the fetal circulation

Svetlana Didenco, Melanie Gillingham, Mitzi D. Go, Scott W. Leonard, Maret G. Traber, Cynthia (Cindy) McEvoy

Research output: Contribution to journalArticle

16 Scopus citations


Background: The transfer of vitamin E across the placenta is limited, but no data exist on the concentrations of vitamin E metabolites carboxyethyl hydroxychromans (α- and γ-CEHCs) in the fetal circulation. Objective: We measured α- and γ-CEHC concentrations in maternal and umbilical cord blood pairs and examined their relations to circulating vitamin E (α- and γ-tocopherol) and maternal dietary vitamin E intake. Design: Healthy, pregnant women were enrolled from Oregon Health and Science University's obstetric clinic (

Original languageEnglish (US)
Pages (from-to)368-373
Number of pages6
JournalAmerican Journal of Clinical Nutrition
Issue number2
Publication statusPublished - Feb 1 2011


ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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