Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a

D. Alexander; R. M. Goodman; M. Gut-Rella; C. Glascock; K. Weymann; L. Friedrich; D. Maddox; P. Ahl-Goy; T. Luntz; E. Ward; J. Ryals

doi:10.1073/pnas.90.15.7327

Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a

D. Alexander, R. M. Goodman, M. Gut-Rella, C. Glascock, K. Weymann, L. Friedrich, D. Maddox, P. Ahl-Goy, T. Luntz, E. Ward, J. Ryals

Research output: Contribution to journal › Article › peer-review

429 Scopus citations

Abstract

Expression of pathogenesis-related protein 1a (PR-1a), a protein of unknown biochemical function, is induced to high levels in tobacco in response to pathogen infection. The induction of PR-1a expression is tightly correlated with the onset of systemic acquired resistance (SAR), a defense response effective against a variety of fungal, viral, and bacterial pathogens. While PR-1a has been postulated to be involved in SAR, and is the most highly expressed of the PR proteins, evidence for its role is lacking. In this report, we demonstrate that constitutive high-level expression of PR- 1a in transgenic tobacco results in tolerance to infection by two oomycete pathogens, Peronospora tabacina and Phytophthora parasitica var. nicotianae.

Original language	English (US)
Pages (from-to)	7327-7331
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	90
Issue number	15
DOIs	https://doi.org/10.1073/pnas.90.15.7327
State	Published - 1993
Externally published	Yes

Keywords

Peronospora tabacina
Phytophthora parasitica
black shank disease
blue mold disease
systemic acquired resistance

ASJC Scopus subject areas

General

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10.1073/pnas.90.15.7327

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Alexander, D., Goodman, R. M., Gut-Rella, M., Glascock, C., Weymann, K., Friedrich, L., Maddox, D., Ahl-Goy, P., Luntz, T., Ward, E., & Ryals, J. (1993). Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a. Proceedings of the National Academy of Sciences of the United States of America, 90(15), 7327-7331. https://doi.org/10.1073/pnas.90.15.7327

Alexander, D, Goodman, RM, Gut-Rella, M, Glascock, C, Weymann, K, Friedrich, L, Maddox, D, Ahl-Goy, P, Luntz, T, Ward, E & Ryals, J 1993, 'Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a', Proceedings of the National Academy of Sciences of the United States of America, vol. 90, no. 15, pp. 7327-7331. https://doi.org/10.1073/pnas.90.15.7327

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abstract = "Expression of pathogenesis-related protein 1a (PR-1a), a protein of unknown biochemical function, is induced to high levels in tobacco in response to pathogen infection. The induction of PR-1a expression is tightly correlated with the onset of systemic acquired resistance (SAR), a defense response effective against a variety of fungal, viral, and bacterial pathogens. While PR-1a has been postulated to be involved in SAR, and is the most highly expressed of the PR proteins, evidence for its role is lacking. In this report, we demonstrate that constitutive high-level expression of PR- 1a in transgenic tobacco results in tolerance to infection by two oomycete pathogens, Peronospora tabacina and Phytophthora parasitica var. nicotianae.",

keywords = "Peronospora tabacina, Phytophthora parasitica, black shank disease, blue mold disease, systemic acquired resistance",

author = "D. Alexander and Goodman, {R. M.} and M. Gut-Rella and C. Glascock and K. Weymann and L. Friedrich and D. Maddox and P. Ahl-Goy and T. Luntz and E. Ward and J. Ryals",

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AU - Alexander, D.

AU - Goodman, R. M.

AU - Gut-Rella, M.

AU - Glascock, C.

AU - Weymann, K.

AU - Friedrich, L.

AU - Maddox, D.

AU - Ahl-Goy, P.

AU - Luntz, T.

AU - Ward, E.

AU - Ryals, J.

PY - 1993

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KW - Peronospora tabacina

KW - Phytophthora parasitica

KW - black shank disease

KW - blue mold disease

KW - systemic acquired resistance

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Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a

Abstract

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