Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a

D. Alexander, R. M. Goodman, M. Gut-Rella, C. Glascock, K. Weymann, L. Friedrich, D. Maddox, P. Ahl-Goy, T. Luntz, E. Ward, J. Ryals

Research output: Contribution to journalArticlepeer-review

396 Scopus citations

Abstract

Expression of pathogenesis-related protein 1a (PR-1a), a protein of unknown biochemical function, is induced to high levels in tobacco in response to pathogen infection. The induction of PR-1a expression is tightly correlated with the onset of systemic acquired resistance (SAR), a defense response effective against a variety of fungal, viral, and bacterial pathogens. While PR-1a has been postulated to be involved in SAR, and is the most highly expressed of the PR proteins, evidence for its role is lacking. In this report, we demonstrate that constitutive high-level expression of PR- 1a in transgenic tobacco results in tolerance to infection by two oomycete pathogens, Peronospora tabacina and Phytophthora parasitica var. nicotianae.

Original languageEnglish (US)
Pages (from-to)7327-7331
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume90
Issue number15
DOIs
StatePublished - 1993

Keywords

  • Peronospora tabacina
  • Phytophthora parasitica
  • black shank disease
  • blue mold disease
  • systemic acquired resistance

ASJC Scopus subject areas

  • General

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