Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives

Chengdong Zhang; Sanjay V. Malhotra

doi:10.1016/j.talanta.2005.03.037

Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives

Chengdong Zhang, Sanjay V. Malhotra

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy]⁺[PF₆] ^- has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase.

Original language	English (US)
Pages (from-to)	560-563
Number of pages	4
Journal	Talanta
Volume	67
Issue number	3
DOIs	https://doi.org/10.1016/j.talanta.2005.03.037
State	Published - Sep 15 2005
Externally published	Yes

Keywords

Acetylcholinesterase
Imidazolium
Ionic liquids
Paraoxon
Pyridinium

ASJC Scopus subject areas

Analytical Chemistry

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10.1016/j.talanta.2005.03.037

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title = "Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives",

abstract = "This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy]+[PF6] - has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase.",

keywords = "Acetylcholinesterase, Imidazolium, Ionic liquids, Paraoxon, Pyridinium",

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AU - Zhang, Chengdong

AU - Malhotra, Sanjay V.

PY - 2005/9/15

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N2 - This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy]+[PF6] - has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase.

AB - This is the first study using ionic liquids (ILs) as additive in the aqueous solvent medium for detection of paraoxon by acetylcholinesterase inhibition method. A systematic comparison of various ILs with organic solvents has been made. The aqueous buffer solution containing ionic liquid ethylpyridinium hexafluorophosphate [EtPy]+[PF6] - has been found to give the best results. The inhibition kinetic follows the first order model. Ionic liquids modified aqueous solutions show the potential to provide a promising and effective medium in detection of paraoxon with acetylcholinesterase.

KW - Acetylcholinesterase

KW - Imidazolium

KW - Ionic liquids

KW - Paraoxon

KW - Pyridinium

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DO - 10.1016/j.talanta.2005.03.037

M3 - Article

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EP - 563

JO - Talanta

JF - Talanta

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ER -

Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives

Abstract

Keywords

ASJC Scopus subject areas

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