Increased fetal cardiac natriuretic peptide secretion in type-1 diabetic pregnancies

Anna Girsen, Minna Ala-Kopsala, Kaarin Mäkikallio, Olli Vuolteenaho, Juha Rasanen

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Background. We hypothesised that human fetal cardiac natriuretic peptide secretion is increased in type-1 diabetic pregnancies with normal placental hemodynamics, and this increase is related to the first trimester maternal glycemic control. Methods. Thirty-two neonates of type-1 diabetic mothers and 60 neonates born after uncomplicated pregnancy and labour (control group) were included in this study. Diabetic pregnancies were divided into two subgroups based on the first trimester HbA1c value. Group 1 pregnancies (n =22) had a good glycemic control (HbA1c

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
JournalActa Obstetricia et Gynecologica Scandinavica
Volume87
Issue number3
DOIs
Publication statusPublished - 2008

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Keywords

  • Cardiac function
  • Heart
  • Hemodynamics
  • Physiology

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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