Inability to alkalinize urine in a patient at risk for tumor lysis syndrome: A case report

Robert Steelman, Mary Frances D. Pate, Patricia Shoun, Kathleen Wachtel, Phyllis Winters Johannes

Research output: Contribution to journalArticle

Abstract

□ This report provides a description and discussion of a 19-year-old, 65-kg male, with a large mediastinal mass, right pleural effusion, and pericardial effusion, requiring urine alkalinization during a propofol infusion. The patient required NaHCO3 boluses, urine pH, electrolyte, arterial blood gas and lactate monitoring, and discontinuation of the propofol. The authors suggest that caution be used when prescribing a propofol infusion for patients who are at risk of tumor lysis syndrome and the need for urine alkalinization.

Original languageEnglish (US)
Pages (from-to)155-158
Number of pages4
JournalPediatric Hematology and Oncology
Volume25
Issue number2
DOIs
StatePublished - Mar 1 2008

Keywords

  • Alkalinization
  • Case report
  • Propofol infusion
  • Urine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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