In vivo retinal blood flow measurement by Fourier domain Doppler optical coherence tomography

Yimin Wang, Ou Tan, David Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The measurement of ocular blood flow is important in studying the pathophysiology and treatment of several leading causes of blindness. We present a method for in vivo human retinal flow measurement using Fourier domain optical coherence tomography. A double circular scanning pattern was used to scan the blood vessels around the optic nerve head 8 times over 2 seconds. The venous flow totaled 36.13 μl/min in the right eye of a volunteer. The flow difference was observed before and after breath holding. The fast flow measurement method did not require any assumption on the flow profile over time or space.

Original languageEnglish (US)
Title of host publicationCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII
DOIs
StatePublished - Apr 21 2008
Externally publishedYes
EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII - San Jose, CA, United States
Duration: Jan 21 2008Jan 23 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6847
ISSN (Print)1605-7422

Other

OtherCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII
CountryUnited States
CitySan Jose, CA
Period1/21/081/23/08

Keywords

  • Blood flow
  • Imaging
  • Optical coherence tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Wang, Y., Tan, O., & Huang, D. (2008). In vivo retinal blood flow measurement by Fourier domain Doppler optical coherence tomography. In Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII [68470G] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6847). https://doi.org/10.1117/12.765320