In-vivo office-based dynamic imaging of vocal cords in awake patients with swept-source optical coherence tomography

Lingfeng Yu, Gangjun Liu, Marc Rubinstein, Arya Saidi, Shuguang Guo, Brian J.F. Wong, Zhongping Chen

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the human larynx during surgical endoscopy. The design of a long GRIN lens based probe capable of capturing images of the human larynx by use of swept-source OCT during a typical office-based laryngoscopy examination is presented. In vivo OCT imaging of the human larynx is demonstrated with 40 fame/second. Dynamic vibration of the vocal folds is recorded to provide not only high-resolution cross-sectional tissue structures but also vibration parameters, such as the vibration frequency and magnitude of the vocal cord, which provide important information for clinical diagnosis and treatment, as well as in fundamental research of the voice. Office-based OCT is a promising imaging modality to study the larynx.

Original languageEnglish (US)
Article number716126
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7161
DOIs
StatePublished - Jun 8 2009
EventPhotonic Therapeutics and Diagnostics V - San Jose, CA, United States
Duration: Jan 24 2009Jan 26 2009

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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