In vivo mapping of cortical columnar networks in the monkey with focal electrical and optical stimulation

Anna Wang Roe, Mykyta M. Chernov, Robert M. Friedman, Gang Chen

Research output: Contribution to journalReview article

10 Scopus citations


There are currently largescale efforts to understand the brain as a connection machine. However, there has been little emphasis on understanding connection patterns between functionally specific cortical columns. Here, we review development and application of focal electrical and optical stimulation methods combined with optical imaging and fMRI mapping in the non-human primate. These new approaches, when applied systematically on a large scale, will elucidate functionally specific intra-areal and interareal network connection patterns. Such functionally specific network data can provide accurate views of brain network topology.

Original languageEnglish (US)
Article numberA135
Pages (from-to)1-11
Number of pages11
JournalFrontiers in Neuroanatomy
Issue numberNovember
StatePublished - Nov 16 2015



  • Cortical column
  • FMRI
  • Infrared neural stimulation
  • Microstimulation
  • Monkey
  • Optical imaging
  • Optical stimulation
  • Optogenetics

ASJC Scopus subject areas

  • Anatomy
  • Neuroscience (miscellaneous)
  • Cellular and Molecular Neuroscience

Cite this