In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Jiechen Yin; Gangjun Liu; Jun Zhang; Lingfeng Yu; Sari Mahon; David Mukai; Matthew Brenner; Zhongping Chen

doi:10.1117/12.841346

In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Jiechen Yin, Gangjun Liu, Jun Zhang, Lingfeng Yu, Sari Mahon, David Mukai, Matthew Brenner, Zhongping Chen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

We report on the feasibility of rapid, high resolution, 3-dimensional swept source optical coherence tomography (3D SSOCT) to detect early airway injury changes following smoke inhalation exposure in a rabbit model. The SSOCT system obtains 3-D helical scanning using a microelectromechanical system (MEMS) motor based endoscope. Real-time 2-D data processing and image display at the speed of 20 frames per second are achieved by adopting the technique of shared-memory parallel computing. Longitudinal images are reconstructed via an image processing algorithm to remove motion artifacts caused by ventilation and pulse. We demonstrate the ability of the SSOCT system to detect increases in tracheal and bronchial airway thickness that occurs shortly after smoke exposure.

Original language	English (US)
Title of host publication	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
DOIs	https://doi.org/10.1117/12.841346
State	Published - 2010
Externally published	Yes
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV - San Francisco, CA, United States Duration: Jan 25 2010 → Jan 27 2010

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7554
ISSN (Print)	1605-7422

Other

Other	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
Country/Territory	United States
City	San Francisco, CA
Period	1/25/10 → 1/27/10

Keywords

3-dimensional imaging
Image processing
Optical coherence tomography

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

Access to Document

10.1117/12.841346

Cite this

Yin, J., Liu, G., Zhang, J., Yu, L., Mahon, S., Mukai, D., Brenner, M., & Chen, Z. (2010). In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV Article 755408 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7554). https://doi.org/10.1117/12.841346

In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography. / Yin, Jiechen; Liu, Gangjun; Zhang, Jun et al.
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV. 2010. 755408 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7554).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yin, J, Liu, G, Zhang, J, Yu, L, Mahon, S, Mukai, D, Brenner, M & Chen, Z 2010, In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography. in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV., 755408, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, San Francisco, CA, United States, 1/25/10. https://doi.org/10.1117/12.841346

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abstract = "We report on the feasibility of rapid, high resolution, 3-dimensional swept source optical coherence tomography (3D SSOCT) to detect early airway injury changes following smoke inhalation exposure in a rabbit model. The SSOCT system obtains 3-D helical scanning using a microelectromechanical system (MEMS) motor based endoscope. Real-time 2-D data processing and image display at the speed of 20 frames per second are achieved by adopting the technique of shared-memory parallel computing. Longitudinal images are reconstructed via an image processing algorithm to remove motion artifacts caused by ventilation and pulse. We demonstrate the ability of the SSOCT system to detect increases in tracheal and bronchial airway thickness that occurs shortly after smoke exposure.",

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AU - Mukai, David

AU - Brenner, Matthew

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AB - We report on the feasibility of rapid, high resolution, 3-dimensional swept source optical coherence tomography (3D SSOCT) to detect early airway injury changes following smoke inhalation exposure in a rabbit model. The SSOCT system obtains 3-D helical scanning using a microelectromechanical system (MEMS) motor based endoscope. Real-time 2-D data processing and image display at the speed of 20 frames per second are achieved by adopting the technique of shared-memory parallel computing. Longitudinal images are reconstructed via an image processing algorithm to remove motion artifacts caused by ventilation and pulse. We demonstrate the ability of the SSOCT system to detect increases in tracheal and bronchial airway thickness that occurs shortly after smoke exposure.

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In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Abstract

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Keywords

ASJC Scopus subject areas

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