In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

Medicine & Life Sciences

• succinic semialdehyde dehydrogenase deficiency 100%
• Neural Stem Cells 61%
• Brain 26%
• In Vitro Techniques 24%
• Succinate-Semialdehyde Dehydrogenase 19%
• Hydroxybutyrates 17%
• Developmental Genes 15%
• Aldehyde Dehydrogenase 14%
• Gene Expression 13%
• Sirolimus 11%
• Superoxides 11%
• Ion Channels 10%
• Hypothalamus 10%
• Transcriptome 10%
• Epilepsy 9%
• Reactive Oxygen Species 8%
• Cell Death 8%
• Phenotype 6%
• Inflammation 6%
• Animals 5%
• Therapeutics 5%

Agriculture & Biology

• neural stem cells 90%
• succinate dehydrogenase (quinone) 64%
• brain 38%
• mice 31%
• therapeutics 21%
• gene expression 16%
• epilepsy 12%
• rapamycin 11%
• aldehyde dehydrogenase 11%
• ion channels 10%
• hypothalamus 9%
• superoxide anion 8%
• ontogeny 8%
• cell death 8%
• inflammation 8%
• reactive oxygen species 7%
• receptors 6%
• phenotype 6%
• animals 3%

Chemical Compounds

• Succinic Semialdehyde 92%
• Developmental 13%
• Cell Death 11%
• Superoxide 10%
• Reactive Oxygen Metabolite 10%
• Ion 4%