In vitro effects of ethanol on primate luteal membranes

exposure of additional gonadotropin receptor sites.

J. L. Cameron, Richard Stouffer

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The presence of 0.8-8.0% (vol/vol) ethanol increased the specific binding of [125I]human luteinizing hormone (hLH) to membrane particulate fractions prepared from the rhesus monkey corpus luteum in a dose-dependent manner. Ethanol increased the number of available gonadotropin binding sites without altering their affinity for LH. These results suggest that (1) there are additional gonadotropin receptors in the macaque corpus luteum which are not detected by conventional in vitro techniques, and (2) ethanol exposes receptors previously unavailable for hormone interaction.

Original languageEnglish (US)
Pages (from-to)1451-1453
Number of pages3
JournalEndocrinology
Volume110
Issue number4
StatePublished - Apr 1982
Externally publishedYes

Fingerprint

Gonadotropin Receptors
Corpus Luteum
Primates
Ethanol
Membranes
Macaca
Luteinizing Hormone
Macaca mulatta
Gonadotropins
Binding Sites
Hormones
In Vitro Techniques

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

In vitro effects of ethanol on primate luteal membranes : exposure of additional gonadotropin receptor sites. / Cameron, J. L.; Stouffer, Richard.

In: Endocrinology, Vol. 110, No. 4, 04.1982, p. 1451-1453.

Research output: Contribution to journalArticle

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