Improving PMTCT uptake in rural South Africa

Stephen M. Weiss; Peltzer Karl; Villar Loubet Olga; Molatelo E. Shikwane; Cook Ryan; Deborah L. Jones

doi:10.1177/2325957413488203

Improving PMTCT uptake in rural South Africa

Stephen M. Weiss, Peltzer Karl, Villar Loubet Olga, Molatelo E. Shikwane, Cook Ryan, Deborah L. Jones

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Introduction: Despite the widespread availability of prevention of mother-to-child transmission (PMTCT) programs, many women in sub-Saharan Africa do not participate in PMTCT. This pilot study aimed to utilize partner participation in an intervention to support PMTCT uptake. Methods: Couples (n = 239) were randomized to receive either a comprehensive couples-based PMTCT intervention or the standard of care. Results: Compared to the standard of care, participants receiving the intervention increased HIV- and PMTCT-related knowledge (F1,474 = 13.94, p = .004) and uptake of PMTCT, as defined by infant medication dosing (74% vs. 46%, χ² = 4.69, p = .03). Discussion: Results indicate that increasing male attendance at antenatal clinic visits may be "necessary but not sufficient" to increase PMTCT uptake. Increasing HIV knowledge of both partners and encouraging active male participation in the PMTCT process through psychoeducational interventions may be a strategy to increase the uptake of PMTCT in South Africa.

Original language	English (US)
Pages (from-to)	269-276
Number of pages	8
Journal	Journal of the International Association of Providers of AIDS Care
Volume	13
Issue number	3
DOIs	https://doi.org/10.1177/2325957413488203
State	Published - 2014
Externally published	Yes

Keywords

PMTCT
South Africa
male involvement

ASJC Scopus subject areas

Immunology
Dermatology
Infectious Diseases

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10.1177/2325957413488203

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title = "Improving PMTCT uptake in rural South Africa",

abstract = "Introduction: Despite the widespread availability of prevention of mother-to-child transmission (PMTCT) programs, many women in sub-Saharan Africa do not participate in PMTCT. This pilot study aimed to utilize partner participation in an intervention to support PMTCT uptake. Methods: Couples (n = 239) were randomized to receive either a comprehensive couples-based PMTCT intervention or the standard of care. Results: Compared to the standard of care, participants receiving the intervention increased HIV- and PMTCT-related knowledge (F1,474 = 13.94, p = .004) and uptake of PMTCT, as defined by infant medication dosing (74% vs. 46%, χ2 = 4.69, p = .03). Discussion: Results indicate that increasing male attendance at antenatal clinic visits may be {"}necessary but not sufficient{"} to increase PMTCT uptake. Increasing HIV knowledge of both partners and encouraging active male participation in the PMTCT process through psychoeducational interventions may be a strategy to increase the uptake of PMTCT in South Africa.",

keywords = "PMTCT, South Africa, male involvement",

author = "Weiss, {Stephen M.} and Peltzer Karl and Olga, {Villar Loubet} and Shikwane, {Molatelo E.} and Cook Ryan and Jones, {Deborah L.}",

note = "Funding Information: This study was funded as a supplement to a center grant by a PEPFAR/NIAID collaboration for advancing implementation science in PMTCT, targeting existing PEPFAR sites. University of Miami Miller School of Medicine Institutional Review Board, Human Sciences Research Council Research Ethics Committee, and the Mpumalanga Provincial Department of Health approvals were obtained prior to the onset of the study. All procedures followed were in accordance with the ethical standards of the review committees mentioned previously and with the Helsinki Declaration of 1975, as revised in 2000. This study protocol is registered at clinicaltrials.gov, number NCT01448512. All participants provided informed consent prior to enrollment and the initiation of study-related procedures. ",

year = "2014",

doi = "10.1177/2325957413488203",

language = "English (US)",

volume = "13",

pages = "269--276",

journal = "Journal of the International Association of Providers of AIDS Care",

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TY - JOUR

T1 - Improving PMTCT uptake in rural South Africa

AU - Weiss, Stephen M.

AU - Karl, Peltzer

AU - Olga, Villar Loubet

AU - Shikwane, Molatelo E.

AU - Ryan, Cook

AU - Jones, Deborah L.

N1 - Funding Information: This study was funded as a supplement to a center grant by a PEPFAR/NIAID collaboration for advancing implementation science in PMTCT, targeting existing PEPFAR sites. University of Miami Miller School of Medicine Institutional Review Board, Human Sciences Research Council Research Ethics Committee, and the Mpumalanga Provincial Department of Health approvals were obtained prior to the onset of the study. All procedures followed were in accordance with the ethical standards of the review committees mentioned previously and with the Helsinki Declaration of 1975, as revised in 2000. This study protocol is registered at clinicaltrials.gov, number NCT01448512. All participants provided informed consent prior to enrollment and the initiation of study-related procedures.

PY - 2014

Y1 - 2014

N2 - Introduction: Despite the widespread availability of prevention of mother-to-child transmission (PMTCT) programs, many women in sub-Saharan Africa do not participate in PMTCT. This pilot study aimed to utilize partner participation in an intervention to support PMTCT uptake. Methods: Couples (n = 239) were randomized to receive either a comprehensive couples-based PMTCT intervention or the standard of care. Results: Compared to the standard of care, participants receiving the intervention increased HIV- and PMTCT-related knowledge (F1,474 = 13.94, p = .004) and uptake of PMTCT, as defined by infant medication dosing (74% vs. 46%, χ2 = 4.69, p = .03). Discussion: Results indicate that increasing male attendance at antenatal clinic visits may be "necessary but not sufficient" to increase PMTCT uptake. Increasing HIV knowledge of both partners and encouraging active male participation in the PMTCT process through psychoeducational interventions may be a strategy to increase the uptake of PMTCT in South Africa.

AB - Introduction: Despite the widespread availability of prevention of mother-to-child transmission (PMTCT) programs, many women in sub-Saharan Africa do not participate in PMTCT. This pilot study aimed to utilize partner participation in an intervention to support PMTCT uptake. Methods: Couples (n = 239) were randomized to receive either a comprehensive couples-based PMTCT intervention or the standard of care. Results: Compared to the standard of care, participants receiving the intervention increased HIV- and PMTCT-related knowledge (F1,474 = 13.94, p = .004) and uptake of PMTCT, as defined by infant medication dosing (74% vs. 46%, χ2 = 4.69, p = .03). Discussion: Results indicate that increasing male attendance at antenatal clinic visits may be "necessary but not sufficient" to increase PMTCT uptake. Increasing HIV knowledge of both partners and encouraging active male participation in the PMTCT process through psychoeducational interventions may be a strategy to increase the uptake of PMTCT in South Africa.

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KW - South Africa

KW - male involvement

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Improving PMTCT uptake in rural South Africa

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