Verbesserung des gleichgewichts durch audiobiofeedback. eine 6-wöchige interventionsstudie mit patienten mit progressiver supranucleärer blickparese

Translated title of the contribution: Improvement of balance after audio-biofeedback: A 6-week intervention study in patients with progressive supranuclear palsy

S. Nicolai, A. Mirelman, T. Herman, A. Zijlstra, Martina Mancini, C. Becker, U. Lindemann, D. Berg, W. Maetzler

Research output: Contribution to journalArticle

25 Scopus citations


Progressive supranuclear palsy (PSP) is a neurodegenerative disease with no sufficient treatment options to date. The most devastating symptom is the loss of balance with consecutive falls. Based on the observation that postural control improved in patients with vestibular dysfunction after audio-biofeedback training, we tested the effects of this training in PSP patients. Eight PSP patients were included into an uncontrolled 6-week intervention trial. The focus of the training was the improvement of posture and dynamic balance by using audio-biofeedback. The device was well accepted. No adverse events occurred. A significant improvement in the Berg Balance Scale was observed (T2 vs. T1, p=0.016), which remained significant at the 4-week follow-up (T3 vs. T1, p=0.008). Significant improvement of the Parkinson's disease questionnaire was demonstrated. No significant changes were found in the Timed Up-and-Go Test, the Five Chair Rise Test, and in specific clinical scales. To our knowledge, the present study is the first to demonstrate that audio-biofeedback training with PSP patients is associated with improvements of balance and psychosocial aspects.

Original languageGerman
Pages (from-to)224-228
Number of pages5
JournalZeitschrift fur Gerontologie und Geriatrie
Issue number4
Publication statusPublished - 2010
Externally publishedYes



  • Intervention
  • Mobility
  • Neurodegenerative disease
  • Postural stability
  • Posture control

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Gerontology
  • Issues, ethics and legal aspects
  • Health(social science)
  • Medicine(all)

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