Improved survival in young women with breast cancer

Benjamin O. Anderson, Ruby T. Senie, John Vetto, George Y. Wong, Beryl McCormick, Patrick I. Borgen

    Research output: Contribution to journalArticle

    41 Citations (Scopus)

    Abstract

    Background: Young age has been hypothesized to be an adverse prognostic factor for women with breast cancer. This association, based on historical data, may not reflect recent advances in breast cancer management. Methods: A retrospective study was conducted of all women age 30 or younger who underwent definitive operation at our institution for primary operable breast carcinoma during one of two consecutive 20-year periods (1950-1969 or 1970-1989). All cancers were restaged according to current staging criteria. Actuarial survival and recurrence-free survival rates from the two patient eras were compared with each other and with published statistics for older breast cancer patients. Results: Eligibility criteria were met by 81 women from the 1950-1969 era and 146 women from the 1970-1989 era. Histologic diagnoses, tumor sizes, incidence of axillary nodal metastases, number of positive nodes, and American Joint Committee on Cancer stage at presentation were similarly distributed in the two eras. Despite these similarities, improved survival (p=0.009) was observed in the later era. Local recurrences were also more common (p

    Original languageEnglish (US)
    Pages (from-to)407-415
    Number of pages9
    JournalAnnals of Surgical Oncology
    Volume2
    Issue number5
    DOIs
    StatePublished - Sep 1995

    Fingerprint

    Breast Neoplasms
    Survival
    Recurrence
    Neoplasms
    Survival Rate
    Retrospective Studies
    Neoplasm Metastasis
    Incidence

    Keywords

    • Breast cancer
    • Chemotherapy
    • Local recurrence
    • Young age

    ASJC Scopus subject areas

    • Surgery
    • Oncology

    Cite this

    Anderson, B. O., Senie, R. T., Vetto, J., Wong, G. Y., McCormick, B., & Borgen, P. I. (1995). Improved survival in young women with breast cancer. Annals of Surgical Oncology, 2(5), 407-415. https://doi.org/10.1007/BF02306373

    Improved survival in young women with breast cancer. / Anderson, Benjamin O.; Senie, Ruby T.; Vetto, John; Wong, George Y.; McCormick, Beryl; Borgen, Patrick I.

    In: Annals of Surgical Oncology, Vol. 2, No. 5, 09.1995, p. 407-415.

    Research output: Contribution to journalArticle

    Anderson, BO, Senie, RT, Vetto, J, Wong, GY, McCormick, B & Borgen, PI 1995, 'Improved survival in young women with breast cancer', Annals of Surgical Oncology, vol. 2, no. 5, pp. 407-415. https://doi.org/10.1007/BF02306373
    Anderson BO, Senie RT, Vetto J, Wong GY, McCormick B, Borgen PI. Improved survival in young women with breast cancer. Annals of Surgical Oncology. 1995 Sep;2(5):407-415. https://doi.org/10.1007/BF02306373
    Anderson, Benjamin O. ; Senie, Ruby T. ; Vetto, John ; Wong, George Y. ; McCormick, Beryl ; Borgen, Patrick I. / Improved survival in young women with breast cancer. In: Annals of Surgical Oncology. 1995 ; Vol. 2, No. 5. pp. 407-415.
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