Impact of sentinel node status and other risk factors on the clinical outcome of head and neck melanoma patients

Stanley P L Leong, Neil A. Accortt, Richard Essner, Merrick Ross, Jeffrey E. Gershenwald, Barbara Pockaj, Harald J. Hoekstra, Carlos Garberoglio, Richard L. White, David Chu, Merrill Biel, Kim Charney, Harold Wanebo, Eli Avisar, John Vetto, Seng Jaw Soong

    Research output: Contribution to journalArticle

    75 Citations (Scopus)

    Abstract

    Objective: To determine the impact of sentinel lymph node (SLN) status and other risk factorsonrecurrence and overall survival in head and neck melanoma patients. Design: The SLN Working Group, based in San Francisco, Calif, with its 11 member centers, the John Wayne Cancer Institute, and The University of Texas M. D. Anderson Cancer Center pooled data on 629 primary head and neck melanoma patients who had selective sentinel lymphadenectomy. A total of 614 subjects were analyzable. All centers obtained internal review board approval and adhered to the Health Insurance Portability and Accountability Act of 1996 regulations. A Cox proportional hazards model was used to identify factors associated with overall and disease-free survival. Setting: Tertiary care medical centers. Main Outcome Measure: Clinical outcome of head and neck melanoma patients undergoing selective sentinel lymphadenectomy. Results: Overall, 10.1% (n=62) of the subjects had at least 1 positive node. Subjects with positive SLN status had significantly thicker tumors (mean thickness, 2.8 vs 2.1 mm; P

    Original languageEnglish (US)
    Pages (from-to)370-373
    Number of pages4
    JournalArchives of Otolaryngology - Head and Neck Surgery
    Volume132
    Issue number4
    DOIs
    StatePublished - Apr 2006

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    Melanoma
    Neck
    Head
    Lymph Node Excision
    Health Insurance Portability and Accountability Act
    Neoplasms
    San Francisco
    Proportional Hazards Models
    Tertiary Care Centers
    Disease-Free Survival
    Outcome Assessment (Health Care)
    Survival
    cyhalothrin
    Sentinel Lymph Node

    ASJC Scopus subject areas

    • Otorhinolaryngology

    Cite this

    Impact of sentinel node status and other risk factors on the clinical outcome of head and neck melanoma patients. / Leong, Stanley P L; Accortt, Neil A.; Essner, Richard; Ross, Merrick; Gershenwald, Jeffrey E.; Pockaj, Barbara; Hoekstra, Harald J.; Garberoglio, Carlos; White, Richard L.; Chu, David; Biel, Merrill; Charney, Kim; Wanebo, Harold; Avisar, Eli; Vetto, John; Soong, Seng Jaw.

    In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 132, No. 4, 04.2006, p. 370-373.

    Research output: Contribution to journalArticle

    Leong, SPL, Accortt, NA, Essner, R, Ross, M, Gershenwald, JE, Pockaj, B, Hoekstra, HJ, Garberoglio, C, White, RL, Chu, D, Biel, M, Charney, K, Wanebo, H, Avisar, E, Vetto, J & Soong, SJ 2006, 'Impact of sentinel node status and other risk factors on the clinical outcome of head and neck melanoma patients', Archives of Otolaryngology - Head and Neck Surgery, vol. 132, no. 4, pp. 370-373. https://doi.org/10.1001/archotol.132.4.370
    Leong, Stanley P L ; Accortt, Neil A. ; Essner, Richard ; Ross, Merrick ; Gershenwald, Jeffrey E. ; Pockaj, Barbara ; Hoekstra, Harald J. ; Garberoglio, Carlos ; White, Richard L. ; Chu, David ; Biel, Merrill ; Charney, Kim ; Wanebo, Harold ; Avisar, Eli ; Vetto, John ; Soong, Seng Jaw. / Impact of sentinel node status and other risk factors on the clinical outcome of head and neck melanoma patients. In: Archives of Otolaryngology - Head and Neck Surgery. 2006 ; Vol. 132, No. 4. pp. 370-373.
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