Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans

Njeri Karanja, Cynthia Morris, Patricia Rufolo, Geoffrey Snyder, D. Roger Illingworth, David A. McCarron

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.

Original languageEnglish (US)
Pages (from-to)900-907
Number of pages8
JournalAmerican Journal of Clinical Nutrition
Volume59
Issue number4
StatePublished - Apr 1994

Fingerprint

lipoproteins
blood lipids
Lipoproteins
Diet
Calcium
Lipids
calcium
Food
nutrients
diet
Riboflavin
Thiamine
placebos
Placebos
Vitamin D
Phosphorus
Magnesium
riboflavin
vitamin D
thiamin

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans. / Karanja, Njeri; Morris, Cynthia; Rufolo, Patricia; Snyder, Geoffrey; Illingworth, D. Roger; McCarron, David A.

In: American Journal of Clinical Nutrition, Vol. 59, No. 4, 04.1994, p. 900-907.

Research output: Contribution to journalArticle

Karanja, N, Morris, C, Rufolo, P, Snyder, G, Illingworth, DR & McCarron, DA 1994, 'Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans', American Journal of Clinical Nutrition, vol. 59, no. 4, pp. 900-907.
Karanja, Njeri ; Morris, Cynthia ; Rufolo, Patricia ; Snyder, Geoffrey ; Illingworth, D. Roger ; McCarron, David A. / Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans. In: American Journal of Clinical Nutrition. 1994 ; Vol. 59, No. 4. pp. 900-907.
@article{075fe925934b41eea24ce089bbe45423,
title = "Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans",
abstract = "This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.",
author = "Njeri Karanja and Cynthia Morris and Patricia Rufolo and Geoffrey Snyder and Illingworth, {D. Roger} and McCarron, {David A.}",
year = "1994",
month = "4",
language = "English (US)",
volume = "59",
pages = "900--907",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "4",

}

TY - JOUR

T1 - Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans

AU - Karanja, Njeri

AU - Morris, Cynthia

AU - Rufolo, Patricia

AU - Snyder, Geoffrey

AU - Illingworth, D. Roger

AU - McCarron, David A.

PY - 1994/4

Y1 - 1994/4

N2 - This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.

AB - This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.

UR - http://www.scopus.com/inward/record.url?scp=0028209945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028209945&partnerID=8YFLogxK

M3 - Article

VL - 59

SP - 900

EP - 907

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 4

ER -