Abstract
This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 900-907 |
| Number of pages | 8 |
| Journal | American Journal of Clinical Nutrition |
| Volume | 59 |
| Issue number | 4 |
| State | Published - Apr 1994 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
Cite this
Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans. / Karanja, Njeri; Morris, Cynthia; Rufolo, Patricia; Snyder, Geoffrey; Illingworth, D. Roger; McCarron, David A.
In: American Journal of Clinical Nutrition, Vol. 59, No. 4, 04.1994, p. 900-907.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Impact of increasing calcium in the diet on nutrient consumption, plasma lipids, and lipoproteins in humans
AU - Karanja, Njeri
AU - Morris, Cynthia
AU - Rufolo, Patricia
AU - Snyder, Geoffrey
AU - Illingworth, D. Roger
AU - McCarron, David A.
PY - 1994/4
Y1 - 1994/4
N2 - This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.
AB - This study examined the feasibility of increasing food-derived calcium to 1500 mg/d and the impact of this change on plasma lipids and nutrient consumption in hypertensive (n = 130) and normotensive (n = 196) participants. Three interventions were applied in a randomized, parallel, placebo-controlled fashion: 1) counseling to increase dietary calcium through food consumption to 1500 mg/d (n = 106), 2) a 1000-mg/d calcium supplement (n = 109), or 3) placebo (n = 111). Plasma lipids were measured before and after 12 wk of intervention whereas nutrient intake was monitored throughout the study. At baseline, hypertensive patients reported lower intakes of carbohydrates, calcium, magnesium, phosphorus, potassium, iron, vitamin D, thiamin, and riboflavin (all P <0.05). They also had lower HDL (P = 0.014) and higher LDL (P <0.05) compared with normotensive subjects. During intervention, calcium, magnesium, phosphorus, potassium, thiamin, riboflavin, and vitamins C and D increased (P <0.01) in the group receiving food calcium but not in the placebo or supplement groups. No changes occurred in plasma lipids or lipoproteins after 12 wk of intervention.
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M3 - Article
VL - 59
SP - 900
EP - 907
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
SN - 0002-9165
IS - 4
ER -