Immune complex nephropathy in mixed connective tissue disease

Robert M. Bennett; Benjamin H. Spargo

doi:10.1016/0002-9343(77)90198-X

Immune complex nephropathy in mixed connective tissue disease

Robert M. Bennett, Benjamin H. Spargo

Research output: Contribution to journal › Article

55 Scopus citations

Abstract

Initial reports on the clinical spectrum of mixed connective tissue disease (MCTD) indicated that renal involvement was uncommon. Four of 20 patients with MCTD underwent renal biopsy and all showed evidence of immune complex trapping with a membranous glomerulonephritis in three patients. Clinically evident renal disease was absent in two patients. These findings suggest that renal involvement in MCTD may be more prevalent than previously indicated.

Original language	English (US)
Pages (from-to)	534-541
Number of pages	8
Journal	The American Journal of Medicine
Volume	63
Issue number	4
DOIs	https://doi.org/10.1016/0002-9343(77)90198-X
State	Published - Oct 1977

ASJC Scopus subject areas

Medicine(all)

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Bennett, R. M., & Spargo, B. H. (1977). Immune complex nephropathy in mixed connective tissue disease. The American Journal of Medicine, 63(4), 534-541. https://doi.org/10.1016/0002-9343(77)90198-X

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abstract = "Initial reports on the clinical spectrum of mixed connective tissue disease (MCTD) indicated that renal involvement was uncommon. Four of 20 patients with MCTD underwent renal biopsy and all showed evidence of immune complex trapping with a membranous glomerulonephritis in three patients. Clinically evident renal disease was absent in two patients. These findings suggest that renal involvement in MCTD may be more prevalent than previously indicated.",

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