Immune complex nephropathy in mixed connective tissue disease

Robert M. Bennett, Benjamin H. Spargo

    Research output: Contribution to journalArticle

    55 Scopus citations

    Abstract

    Initial reports on the clinical spectrum of mixed connective tissue disease (MCTD) indicated that renal involvement was uncommon. Four of 20 patients with MCTD underwent renal biopsy and all showed evidence of immune complex trapping with a membranous glomerulonephritis in three patients. Clinically evident renal disease was absent in two patients. These findings suggest that renal involvement in MCTD may be more prevalent than previously indicated.

    Original languageEnglish (US)
    Pages (from-to)534-541
    Number of pages8
    JournalThe American Journal of Medicine
    Volume63
    Issue number4
    DOIs
    StatePublished - Oct 1977

    ASJC Scopus subject areas

    • Medicine(all)

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