Imaging tissues with a polarized light video camera

S. L. Jacques, K. Lee

Research output: Contribution to journalConference article

9 Scopus citations

Abstract

A method for imaging the superficial epidermal and papillary dermal layers of the skin is needed when assessing many skin lesions. We have developed an imaging modality using a video camera whose mechanism of contrast is the reflectance of polarized light from superficial skin. By selecting only polarized light to create the image, one rejects the large amount of diffusely reflected light from the deeper dermis. The specular reflectance (or glare) from the skin surface is also avoided in the setup. The resulting polarization picture maximally accents the details of the superficial layer of the skin and removes the effects of melanin pigmentation from the image. For example, freckels simply disappear and nevi lose their dark pigmentation to reveal the details of abnormal cellular growth. An initial clinical study demonstrated that the polarization camera could identify the margins of sclerosing basal cell carcinoma while the eye of the doctor underestimated the margin estimate. The camera identified an 11-mm-diameter lesion while the unaided eye identified a 6-mm-diameter lesion.

Original languageEnglish (US)
Pages (from-to)68-74
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3863
StatePublished - Dec 1 1999
EventProceedings of the 1999 International Conference on Biomedical Optics (BMO'99) - Wuhan, China
Duration: Oct 25 1999Oct 27 1999

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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