TY - JOUR
T1 - Imaging serpiginous choroidopathy with spectral domain optical coherence tomography
AU - Punjabi, Omar S.
AU - Rich, Ryan
AU - Davis, Janet L.
AU - Gregori, Giovanni
AU - Flynn, Harry W.
AU - Lujan, Brandon J.
AU - Rosenfeld, Philip J.
AU - Puliafito, Carmen A.
PY - 2008
Y1 - 2008
N2 - The use of spectral domain optical coherence tomography (SD-OCT) in the study of chronic serpiginous choroiditis was evaluated. Two patients with chronic serpiginous choroiditis were imaged using two prototype SD-OCT systems (6-μm axial resolution). Raster scans covering 6 × 6 × 2-mm regions of the retina were obtained, enabling the study of different retinal cross-sectional images. Thickness maps were obtained after segmentation of retinal layers, which could be compared with those on follow-up. SD-OCT allowed the visualization of the cross-sectional retinal architecture at different horizontal positions. Superimposition of SD-OCT generated reconstructed fundus images with fundus photographs provided accurate images registration. Segmentation of retinal layers provided thickness maps and higher-density improved visualization of photoreceptor layer, cysts, and atrophy, which was useful in following change in disease activity over time. The researchers concluded that SD-OCT is a useful tool to study disease morphology and follow-up of chronic serpiginous choroiditis.
AB - The use of spectral domain optical coherence tomography (SD-OCT) in the study of chronic serpiginous choroiditis was evaluated. Two patients with chronic serpiginous choroiditis were imaged using two prototype SD-OCT systems (6-μm axial resolution). Raster scans covering 6 × 6 × 2-mm regions of the retina were obtained, enabling the study of different retinal cross-sectional images. Thickness maps were obtained after segmentation of retinal layers, which could be compared with those on follow-up. SD-OCT allowed the visualization of the cross-sectional retinal architecture at different horizontal positions. Superimposition of SD-OCT generated reconstructed fundus images with fundus photographs provided accurate images registration. Segmentation of retinal layers provided thickness maps and higher-density improved visualization of photoreceptor layer, cysts, and atrophy, which was useful in following change in disease activity over time. The researchers concluded that SD-OCT is a useful tool to study disease morphology and follow-up of chronic serpiginous choroiditis.
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U2 - 10.3928/15428877-20080715-05
DO - 10.3928/15428877-20080715-05
M3 - Article
C2 - 18777879
AN - SCOPUS:51349121104
SN - 1542-8877
VL - 39
SP - S95-S98
JO - Ophthalmic Surgery Lasers and Imaging
JF - Ophthalmic Surgery Lasers and Imaging
IS - 4 SUPPL.
ER -