@inproceedings{c20649d80ea745fc886a4ab08812a4e9,
title = "Imaging organ of Corti vibration using Fourier-domain OCT",
abstract = "Measuring the sound stimulated vibration from various structures in the organ of Corti is important in understanding how the small vibrations are amplified and detected. In this study we examine the feasibility of using phase-sensitive Fourier domain optical coherence tomography (PSFD-OCT) to measure vibration of the cellular structures of the organ of Corti. PSFD-OCT is a low coherence interferrometry system where the interferrogram is detected as a function of wavelength. The phase of the Fourier transformation of the detected spectra contains path deference (between the sample arm and the reference arm) information of the interferometer. In PSFD-OCT this phase is measured as a function of time and thus any time dependent change in the path difference between the sample arm and the reference arm can be detected. In the experiment, we used an in vitro preparation of the guinea pig cochlea and made a surgical opening at the apical end to access the organ of Corti. By applying tones with different frequencies via the intact middle ear, we recorded the structural vibration inside the organ of Corti. Vibration amplitude and phase of different substructures were mapped on a cross-section view of the organ of Corti. Although the measurements were made at the apical turn of the cochlea, it will be possible to make vibration measurement from various turns of the cochlea. The noise floor of the system was 0.3 nm, calibrated using a piezo stack as a calibrator.",
keywords = "cochlear vibration, low coherence interferometry, optical coherence tomography, phase-sensitive Fourier-domain OCT",
author = "Niloy Choudhury and Fangyi Chen and Anders Fridberger and Dingjun Zha and Jacques, {Steven L.} and Wang, {Ruikang K.} and Nuttall, {Alfred L.}",
year = "2011",
doi = "10.1063/1.3658117",
language = "English (US)",
isbn = "9780735409750",
series = "AIP Conference Proceedings",
pages = "391--395",
booktitle = "What Fire is in Mine Ears",
note = "11th International Mechanics of Hearing Workshop - What Fire is in Mine Ears: Progress in Auditory Biomechanics ; Conference date: 16-07-2011 Through 22-07-2011",
}