Imaging optically induced neural activity in the brain

Anita Mahadevan-Jansen, Jonathan M. Cayce, Robert Friedman, Anna W. Roe, Peter E. Konrad, Elizabeth Hillman, E. Duco Jansen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Infrared neural stimulation (INS) is well characterized for the peripheral nervous system; however, translation to the central nervous system (CNS) presents a new setof challenges which require us to consider different anatomy, multiple cell types, and the physiology associated with structures in the CNS. This study presents ourfirst attempt to translate INS to in vivo stimulation of the CNSand to image the related response. The results from this study show that INS generates intrinsic optical signals of similar magnitude and shape associated with well characterized mechanical stimuli. The implications of this work could lead to neural implants which allows for single cell stimulation making it possible to design closed loop neural prosthetics.

Original languageEnglish (US)
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages3379-3381
Number of pages3
DOIs
StatePublished - Dec 1 2010
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: Aug 31 2010Sep 4 2010

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period8/31/109/4/10

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ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Health Informatics

Cite this

Mahadevan-Jansen, A., Cayce, J. M., Friedman, R., Roe, A. W., Konrad, P. E., Hillman, E., & Jansen, E. D. (2010). Imaging optically induced neural activity in the brain. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 3379-3381). [5627920] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). https://doi.org/10.1109/IEMBS.2010.5627920