Imaging of port wine stain lesions using a multi-sensor photoacoustic probe

John A. Viator, Steven Jacques, Guillermo Aguilar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Successful treatment of port wine stain (PWS) birthmarks in human skin utilizes cryogen spray cooling (CSC) in conjunction with laser treatment. CSC pre-cools the epidermis to protect it from subsequent laser irradiation which raises the temperature of both the epidermis and the deeper PWS. As the epidermal temperature is depressed by cryogen, damage to the skin surface is minimized while the PWS reaches temperatures sufficient to permanently damage the lesion. In order to optimize cooling and laser heating dosages and to properly guide laser therapy, the spatial relationship of epidermal melanin and PWS must be known. Photoacoustic depth profiling of human skin uses low energy, nanosecond pulses of laser light to induce acoustic waves in optically absorbing media, such as blood and melanin. We used a 532 nm Nd:YAG laser to measure total epidermal melanin content in human skin, comparing the results with visible reflectance spectroscopy. Furthermore, we performed numerical simulations of photoacoustic generation in skin, showing that a hemisperical acoustic sensor array could be used to reconstruct the rete pattern of epidermal melanin in the basal layer. Finally, we built a hemispherical probe for use in future experiments for imaging of human skin.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
PublisherAmerican Society of Mechanical Engineers (ASME)
Pages719-723
Number of pages5
Volume375
Edition1
DOIs
StatePublished - 2004
Event2004 ASME International Mechanical Engineering Congress and Exposition, IMECE - Anaheim, CA, United States
Duration: Nov 13 2004Nov 19 2004

Other

Other2004 ASME International Mechanical Engineering Congress and Exposition, IMECE
CountryUnited States
CityAnaheim, CA
Period11/13/0411/19/04

Fingerprint

Wine
Photoacoustic effect
Melanin
Skin
Coloring Agents
Melanins
Imaging techniques
Sensors
Lasers
Cooling
Laser heating
Depth profiling
Sensor arrays
Laser beam effects
Temperature
Laser pulses
Blood
Acoustics
Acoustic waves
Spectroscopy

ASJC Scopus subject areas

  • Mechanical Engineering
  • Fluid Flow and Transfer Processes

Cite this

Viator, J. A., Jacques, S., & Aguilar, G. (2004). Imaging of port wine stain lesions using a multi-sensor photoacoustic probe. In American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD (1 ed., Vol. 375, pp. 719-723). [IMECE2004-60872] American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/IMECE2004-60872

Imaging of port wine stain lesions using a multi-sensor photoacoustic probe. / Viator, John A.; Jacques, Steven; Aguilar, Guillermo.

American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 375 1. ed. American Society of Mechanical Engineers (ASME), 2004. p. 719-723 IMECE2004-60872.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Viator, JA, Jacques, S & Aguilar, G 2004, Imaging of port wine stain lesions using a multi-sensor photoacoustic probe. in American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. 1 edn, vol. 375, IMECE2004-60872, American Society of Mechanical Engineers (ASME), pp. 719-723, 2004 ASME International Mechanical Engineering Congress and Exposition, IMECE, Anaheim, CA, United States, 11/13/04. https://doi.org/10.1115/IMECE2004-60872
Viator JA, Jacques S, Aguilar G. Imaging of port wine stain lesions using a multi-sensor photoacoustic probe. In American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. 1 ed. Vol. 375. American Society of Mechanical Engineers (ASME). 2004. p. 719-723. IMECE2004-60872 https://doi.org/10.1115/IMECE2004-60872
Viator, John A. ; Jacques, Steven ; Aguilar, Guillermo. / Imaging of port wine stain lesions using a multi-sensor photoacoustic probe. American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 375 1. ed. American Society of Mechanical Engineers (ASME), 2004. pp. 719-723
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