Abstract
Prenatal exposure to marijuana may lead to epigenetic alterations in the placenta and fetal brain, affecting short- and long-term offspring health. This Viewpoint addresses the critical need to study and characterize the impact of maternal marijuana use and consequences of in utero exposure on later development and health. We highlight the development of new PET imaging tools and the opportunity for longitudinal in vivo non-human primate studies to help elucidate epigenetic changes resulting from prenatal marijuana exposure throughout gestation.
Original language | English (US) |
---|---|
Pages (from-to) | 1466-1468 |
Number of pages | 3 |
Journal | ACS Chemical Neuroscience |
Volume | 12 |
Issue number | 9 |
DOIs | |
State | Published - May 5 2021 |
Keywords
- Epigenetics
- THC
- delta-9-tetrahydrocannabinol
- histone deacetylase
- marijuana
- positron emission tomography
- pregnancy
ASJC Scopus subject areas
- Biochemistry
- Physiology
- Cognitive Neuroscience
- Cell Biology