Hematogeneous spread of primary neoplasm can result in central nervous system (CNS) disease burde various anatomically distinct regions; calvarial, pachymeningeal, leptomeningeal, and intraparenchymal. The choice of imaging modality is dependent on the individual clinical situation, but, largely depends on the patients overall clinical status and the information needed to make . Contrastenhanced magnetic resonance (MR) imaging is the preferred imaging modality; however, computed tomography (CT) is often utilized as the firstpass screening modality disease. Despite the superior soft tissue resolution, multiplanar capability, and of MR imaging, T1-and T2-weighted sequences are limited to delineating morphologic of tissues by tumor. Several physiology based MR imaging sequences have which compliment anatomic MR imaging. Proton magnetic resonance spectroscopic susceptibility contrastenhanced perfusionweighted imaging are two which add additional diagnostic information allowing for improved tumor characterization. Common pitfalls in evaluating for metastatic disease burden include the misidentification -neoplastic hematomas, remote microvascular ischemia, and acute onset of ischemic stroke. pediatric population, CNS metastases are rare; however, the onset of acute neurological a child with known primary tumor should prompt imaging of the neuroaxis.
|Original language||English (US)|
|Title of host publication||Current and Future Management of Brain Metastasis|
|Publisher||S. Karger AG|
|Number of pages||19|
|ISBN (Print)||9783805596183, 9783805596176|
|Publication status||Published - Jan 10 2012|
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