@inproceedings{f34692020e0d47b39425ca5af7b7374c,
title = "IGFs and IGF binding proteins in human breast cancer cell lines",
abstract = "We demonstrated that these hBCCL have both Type 1 and 2 IGF receptors and, in data not shown, can respond to small amounts of exogenous IGFs. These cells also secrete a variety of different IGF-BPs into CM. While many of these secreted IGF-BPs appear related to the three recently characterized human IGF-BPs, the identity of the prominent 24 kD band remains unknown. It is clear that these high affinity IGF-BPs can confound attempts to detect either IGF-I or -II by radioligand assay and must be carefully removed before such assays. While it is tempting to hypothesize that these IGF-BPs act in a paracrine or autocrine manner to modulate the effects of IGF-I and -II, the physiological role of these IGF-BPs remains unclear.",
author = "Wilson, {D. M.} and Deleon, {D. D.} and B. Bakker and G. Lamson and Rosenfeld, {R. G.}",
year = "1989",
language = "English (US)",
isbn = "0444811834",
series = "Insuline-like Growth Factor binding proteins: proceedings of a workshop on Insuline-like Growth Factor binding proteins. ICS881",
publisher = "Elsevier Science Publishers B.V.",
pages = "241--247",
editor = "S.L.S. Drop and R.L. Hintz and S.L.S. Drop and R.L. Hintz",
booktitle = "Insuline-like Growth Factor binding proteins",
note = "A workshop on Insuline-like Growth Factor binding proteins ; Conference date: 17-06-1989 Through 19-06-1989",
}