HYPERCALCIURIE IDIOPATHIQUE: EFFET D'UNE CARENCE AIGUE EN PHOSPHORE

Translated title of the contribution: Idiopathic hypercalciuria: Effects of acute phosphorus deficiency

A. Ulmann, S. Dard, B. Lacour, M. Rieu, J. B. Roullet, J. Gueris, J. L. Funck-Brentano

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

11 patients with kidney stone disease and idiopathic hypercalciuria (urinary calcium above 4 mg/kg/j), without phosphorus renal leak and 6 control subjects were put for 3 days on a diet containing 1 g calcium and 1 phosphorus daily (period A), and then for 4 days on a diet containing 1 g calcium, 450 mg phosphorus and 3 g aluminium hydroxide daily (period B). During period A, no significant difference in blood calcium, phosphorus and magnesium, phosphaturia, rate of phosphorus reabsorption (RPR) and ratio maximum RPR/creatinine clearance was found between the two groups. After 2 days on a low phosphate diet (period B) the blood phosphorus decreased significantly in the hypercalciuric patients thus revealing a latent abnormality in the retention of phosphates in them. This abnormality could play an important role in the pathogenesis of hypercalciuria.

Translated title of the contributionIdiopathic hypercalciuria: Effects of acute phosphorus deficiency
Original languageFrench
Pages (from-to)3619-3622
Number of pages4
JournalNouvelle Presse Medicale
Volume8
Issue number44
StatePublished - Dec 1 1979

ASJC Scopus subject areas

  • Medicine(all)

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    Ulmann, A., Dard, S., Lacour, B., Rieu, M., Roullet, J. B., Gueris, J., & Funck-Brentano, J. L. (1979). HYPERCALCIURIE IDIOPATHIQUE: EFFET D'UNE CARENCE AIGUE EN PHOSPHORE. Nouvelle Presse Medicale, 8(44), 3619-3622.