Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays

Richard Grant, Brandon Keele, La Rene Kuller, Robin Watanabe, Alex Perret, Jeremy Smedley

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Simian betaretroviruses include the well-known exogenous simian retroviruses (SRV-1 through SRV-8), and some closely related simian endogenous retroviruses (SERV). Here, we characterized two new viral genomes, which appear to represent novel SERVs but have characteristics of both SRV and SERV highlighting the need to develop new assays providing molecular and serologic differentiation of SERV and SRV to avoid false positives.

Original languageEnglish (US)
Pages (from-to)158-161
Number of pages4
JournalJournal of medical primatology
Volume46
Issue number4
DOIs
StatePublished - Aug 2017

Keywords

  • Macaque
  • PCR
  • Specific Pathogen-Free (SPF)
  • sequencing
  • western blot

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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