Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays

Richard Grant, Brandon Keele, La Rene Kuller, Robin Watanabe, Alex Perret, Jeremy Smedley

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Simian betaretroviruses include the well-known exogenous simian retroviruses (SRV-1 through SRV-8), and some closely related simian endogenous retroviruses (SERV). Here, we characterized two new viral genomes, which appear to represent novel SERVs but have characteristics of both SRV and SERV highlighting the need to develop new assays providing molecular and serologic differentiation of SERV and SRV to avoid false positives.

Original languageEnglish (US)
Pages (from-to)158-161
Number of pages4
JournalJournal of Medical Primatology
Volume46
Issue number4
DOIs
StatePublished - Aug 1 2017
Externally publishedYes

Fingerprint

Simian Retroviruses
Retroviridae
Endogenous Retroviruses
assays
Mason-Pfizer monkey virus
Betaretrovirus
Viral Genome
genome

Keywords

  • Macaque
  • PCR
  • sequencing
  • Specific Pathogen-Free (SPF)
  • western blot

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays. / Grant, Richard; Keele, Brandon; Kuller, La Rene; Watanabe, Robin; Perret, Alex; Smedley, Jeremy.

In: Journal of Medical Primatology, Vol. 46, No. 4, 01.08.2017, p. 158-161.

Research output: Contribution to journalArticle

Grant, Richard ; Keele, Brandon ; Kuller, La Rene ; Watanabe, Robin ; Perret, Alex ; Smedley, Jeremy. / Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays. In: Journal of Medical Primatology. 2017 ; Vol. 46, No. 4. pp. 158-161.
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