Identification of insulin-uke growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight igf-bp in human seminal plasma

Ron G. Rosenfeld, Hung Pham, Youngman Oh, George Lamson, Linda C. Giudice

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

Three distinct binding proteins for the insulin-like growth factors (IGF-BPs) have recently had their cDNAs cloned and sequenced. We have evaluated IGF-BP expression in normal, oligospermic and azospermic human seminal plasma (SP), and have identified IGF-BP-2 in all samples. Additionally, SP contains a non-glycosylated low molecular weight IGF-BP (24K), which does not appear to be structurally or immunologically related to IGF-BP-1, -2 or -3.

Original languageEnglish (US)
Pages (from-to)551-553
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume70
Issue number2
DOIs
StatePublished - Feb 1990

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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