Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma

Ronald (Ron) Rosenfeld, Hung Pham, Youngman Oh, George Lamson, Linda C. Giudice

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Three distinct binding proteins for the insulin-like growth factors (IGF-BPs) have recently had their cDNAs cloned and sequenced. We have evaluated IGF-BP expression in normal, oligospermic and azospermic human seminal plasma (SP), and have identified IGF-BP-2 in all samples. Additionally, SP contains a non-glycosylated low molecular weight IGF-BP (24K), which does not appear to be structurally or immunologically related to IGF-BP-1, -2 or -3.

Original languageEnglish (US)
Pages (from-to)551-553
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume70
Issue number2
StatePublished - 1990
Externally publishedYes

Fingerprint

Insulin-Like Growth Factor Binding Protein 2
Plasma (human)
Insulin-Like Growth Factor Binding Proteins
Semen
Complementary DNA
Molecular Weight
Molecular weight
Plasmas
Insulin-Like Growth Factor I

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma. / Rosenfeld, Ronald (Ron); Pham, Hung; Oh, Youngman; Lamson, George; Giudice, Linda C.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 70, No. 2, 1990, p. 551-553.

Research output: Contribution to journalArticle

Rosenfeld, Ronald (Ron) ; Pham, Hung ; Oh, Youngman ; Lamson, George ; Giudice, Linda C. / Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma. In: Journal of Clinical Endocrinology and Metabolism. 1990 ; Vol. 70, No. 2. pp. 551-553.
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