Ictal spiking patterns recorded from temporal depth electrodes predict good outcome after anterior temporal lobectomy

Lori A. Schuh, Thomas R. Henry, Donald (Don) Ross, Brien J. Smith, Kost Elisevich, Ivo Drury

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose: Investigators have shown that the presence of ictal spiking (IS) recorded from temporal depth electrodes is associated with mesial temporal sclerosis (MTS). We investigated the relation of IS to seizure control and pathology after anterior temporal lobectomy (ATL). Methods: All patients undergoing intracranial ictal monitoring from a single institution since 1989 were identified. Those who did not undergo ATL or had postoperative follow-up of 2, Fisher exact test, and Wilcoxon rank sum. Results: Forty patients with 571 seizures were reviewed. In 292 seizures from 32 patients, IS was seen. Outcomes were 24 class I (22 with IS), five class II (four with IS), three class III (one with IS), seven class IV (four with IS), and one lost to follow-up (with IS). Pathologic review revealed 25 with MTS, 22 of whom had IS. The presence of IS was associated with class I outcomes (p = 0.04), but not MTS (p = 0.06). Patients with class I outcomes had a significantly greater proportion of seizures with IS (mean, 0.58 ± 0.3) compared with other outcomes (mean, 0.30 ± 0.3, p = 0.02). Conclusions: The presence of IS and higher proportion of seizures with IS correlated with good seizure outcome after ATL. This information may be used in preoperative counseling.

Original languageEnglish (US)
Pages (from-to)316-319
Number of pages4
JournalEpilepsia
Volume41
Issue number3
StatePublished - 2000
Externally publishedYes

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Anterior Temporal Lobectomy
Electrodes
Stroke
Seizures
Sclerosis
Nonparametric Statistics
Lost to Follow-Up

Keywords

  • EEG
  • Implanted electrodes
  • Mesial temporal sclerosis
  • Seizure outcome
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Schuh, L. A., Henry, T. R., Ross, D. D., Smith, B. J., Elisevich, K., & Drury, I. (2000). Ictal spiking patterns recorded from temporal depth electrodes predict good outcome after anterior temporal lobectomy. Epilepsia, 41(3), 316-319.

Ictal spiking patterns recorded from temporal depth electrodes predict good outcome after anterior temporal lobectomy. / Schuh, Lori A.; Henry, Thomas R.; Ross, Donald (Don); Smith, Brien J.; Elisevich, Kost; Drury, Ivo.

In: Epilepsia, Vol. 41, No. 3, 2000, p. 316-319.

Research output: Contribution to journalArticle

Schuh, LA, Henry, TR, Ross, DD, Smith, BJ, Elisevich, K & Drury, I 2000, 'Ictal spiking patterns recorded from temporal depth electrodes predict good outcome after anterior temporal lobectomy', Epilepsia, vol. 41, no. 3, pp. 316-319.
Schuh, Lori A. ; Henry, Thomas R. ; Ross, Donald (Don) ; Smith, Brien J. ; Elisevich, Kost ; Drury, Ivo. / Ictal spiking patterns recorded from temporal depth electrodes predict good outcome after anterior temporal lobectomy. In: Epilepsia. 2000 ; Vol. 41, No. 3. pp. 316-319.
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