Iatrogenic arterial spasm relieved by intraarterial mannitol infusion

David Fortin, Eva Osztie, Edward Neuwelt

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Catheter placement for blood brain-barrier disruption and enhanced chemotherapy delivery can sometimes trigger arterial spasm of moderate-to- severe degree. A slow infusion of a small quantity of intraarterially administered mannitol (10 mL of 25% mannitol) was evaluated as a means to obtain a rapid resolution of catheter placement-induced spasm. We prospectively report 12 consecutive cases of blood brain-barrier disruption among patients who developed catheter placement-induced spasm that was treated by this means without side effects, resulting in rapid resolution of spasm.

Original languageEnglish (US)
Pages (from-to)968-970
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume21
Issue number5
StatePublished - 2000

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Intra Arterial Infusions
Spasm
Mannitol
Catheters
Blood-Brain Barrier
Drug Therapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Iatrogenic arterial spasm relieved by intraarterial mannitol infusion. / Fortin, David; Osztie, Eva; Neuwelt, Edward.

In: American Journal of Neuroradiology, Vol. 21, No. 5, 2000, p. 968-970.

Research output: Contribution to journalArticle

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