Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation

Domenico Tupone; Shaun Morrison

doi:10.4161/temp.29916

Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation

Domenico Tupone, Shaun Morrison

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

Original language	English (US)
Pages (from-to)	89-91
Number of pages	3
Journal	Temperature
Volume	1
Issue number	2
DOIs	https://doi.org/10.4161/temp.29916
State	Published - Sep 30 2014

Keywords

Adenosine
brown adipose tissue
hibernation
thermoregulation
torpor

ASJC Scopus subject areas

Physiology
Physiology (medical)

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10.4161/temp.29916

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title = "Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation",

abstract = "Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.",

keywords = "Adenosine, brown adipose tissue, hibernation, thermoregulation, torpor",

author = "Domenico Tupone and Shaun Morrison",

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N2 - Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

AB - Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

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KW - hibernation

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KW - torpor

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Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation

Abstract

Keywords

ASJC Scopus subject areas

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