Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

Original languageEnglish (US)
Pages (from-to)89-91
Number of pages3
JournalTemperature
Volume1
Issue number2
DOIs
StatePublished - Sep 30 2014

Fingerprint

Torpor
Adenosine A1 Receptors
Induced Hypothermia
Body Temperature Regulation
Intracranial Hemorrhages
Hypothermia
Brain Ischemia
Pharmacology
Pathology

Keywords

  • Adenosine
  • brown adipose tissue
  • hibernation
  • thermoregulation
  • torpor

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

@article{4748f335942d4e0f8a8e2964563b2bcc,
title = "Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation",
abstract = "Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.",
keywords = "Adenosine, brown adipose tissue, hibernation, thermoregulation, torpor",
author = "Domenico Tupone and Shaun Morrison",
year = "2014",
month = "9",
day = "30",
doi = "10.4161/temp.29916",
language = "English (US)",
volume = "1",
pages = "89--91",
journal = "Temperature",
issn = "2332-8940",
publisher = "Taylor and Francis Ltd.",
number = "2",

}

TY - JOUR

T1 - Hypothermia, torpor and the fundamental importance of understanding the central control of thermoregulation

AU - Tupone, Domenico

AU - Morrison, Shaun

PY - 2014/9/30

Y1 - 2014/9/30

N2 - Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

AB - Activation of central adenosine A1 receptors in the rat, a non-hibernating species, mimics the physiological characteristics of torpor and could thus represent a basis for the development of pharmacological approaches to induce therapeutic hypothermia in pathologies such as brain hemorrhage and ischemia, and to facilitate long-term space travel.

KW - Adenosine

KW - brown adipose tissue

KW - hibernation

KW - thermoregulation

KW - torpor

UR - http://www.scopus.com/inward/record.url?scp=85019974256&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019974256&partnerID=8YFLogxK

U2 - 10.4161/temp.29916

DO - 10.4161/temp.29916

M3 - Article

VL - 1

SP - 89

EP - 91

JO - Temperature

JF - Temperature

SN - 2332-8940

IS - 2

ER -