Hypotension harry: Fatal Forty DDI: Nicardipine, clarithromycin, CYP3A4

Matthew Hart; Bryan J. Read; Wayne T. Nicholson; Toby N. Weingarten

doi:10.1007/978-1-4614-7495-1_126

Hypotension harry: Fatal Forty DDI: Nicardipine, clarithromycin, CYP3A4

Matthew Hart, Bryan J. Read, Wayne T. Nicholson, Toby N. Weingarten

Anesthesiology and Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses a pharmacokinetic interaction between nifedipine and clarithromycin resulting in hypotension. Nifedipine is a cytochrome P450 3A4 substrate and clarithromycin is a 3A4 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	573-575
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_126
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_126

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abstract = "This case discusses a pharmacokinetic interaction between nifedipine and clarithromycin resulting in hypotension. Nifedipine is a cytochrome P450 3A4 substrate and clarithromycin is a 3A4 inhibitor.",

author = "Matthew Hart and Read, {Bryan J.} and Nicholson, {Wayne T.} and Weingarten, {Toby N.}",

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Hypotension harry: Fatal Forty DDI: Nicardipine, clarithromycin, CYP3A4

Abstract

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