Hypoglycemic potentials of methanolic extracts of selected plant foods in alloxanized mice

O. O. Ogundipe, J. O. Moody, T. O. Akinyemi, A. Raman

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Crude methanolic extracts of five selected edible plant foods were tested for hypoglycemic activity in alloxanized mice. Fasting blood sugar levels were reduced significantly at differing rates. The order of their antidiabetic activity were H. sabdariffa, A. occidentalis, S. americanum, V. amygdalina, G. latifolium, H. sabdariffa, A. occidentalis and S. americanum, utilized at a dose of 100 mg/kg, had similar activity as chlorpropamide (5 mg/kg), which was used as a reference standard, in that they reduced blood sugar levels in mice below the initial values.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalPlant Foods for Human Nutrition
Volume58
Issue number3
DOIs
StatePublished - Jan 1 2003

Keywords

  • Alloxanized mice
  • Hypoglycemic activity
  • Plant foods

ASJC Scopus subject areas

  • Food Science
  • Chemistry (miscellaneous)

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