Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine

Daniel M. Gibbs

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Abstract

Basilar artery blood flow was measured by transcranial Doppler ultrasonography before and during hyperventilation in nine patients with panic disorder and nine normal comparison subjects. The hyperventilation-induced decrease in basilar artery blood flow was significantly greater in patients with panic attacks than in comparison subjects. Two patients with decreases in basilar flow greater than 80% were successfully treated with nimodipine, a centrally active calcium channel blocker.

Original languageEnglish (US)
Pages (from-to)1589-1591
Number of pages3
JournalAmerican Journal of Psychiatry
Volume149
Issue number11
Publication statusPublished - 1992
Externally publishedYes

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ASJC Scopus subject areas

  • Psychiatry and Mental health

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