Six pregnancies occurring in four mothers with hyperparathyroidism have been presented. Four of the pregnancies were completed without therapy; in two, parathyroidectomy was performed. The outcome of each of the pregnancies was satisfactory. The 49 cases previously reported are reviewed. This experience demonstrates that parathyroidectomy is indicated if the mother has symptomatic hypercalcemia, and it can be safely performed during the second trimester. Pregnant women with mild, asymptomatic hypercalcemia may be followed nonoperatively during pregnancy with satisfactory outcome to both the mother and fetus.
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